Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| PAAD | Pancreatic adenocarcinoma | S31P | Missense | 7 |
| BLCA | Bladder urothelial carcinoma | S31P | Missense | 2 |
| COAD | Colon adenocarcinoma | I250T | Missense | 2 |
| THCA | Thyroid carcinoma | S31P | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E93K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G59S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I313V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q52E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V223M | Missense | 1 |
| BRCA | Breast invasive carcinoma | D74E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R394C | Missense | 1 |
| CESC | Cervical and endocervical cancers | L197L | Silent | 1 |
| COAD | Colon adenocarcinoma | A129D | Missense | 1 |
| COAD | Colon adenocarcinoma | A129T | Missense | 1 |
| COAD | Colon adenocarcinoma | A17A | Silent | 1 |
| COAD | Colon adenocarcinoma | D252D | Silent | 1 |
| COAD | Colon adenocarcinoma | E353D | Missense | 1 |
| COAD | Colon adenocarcinoma | G119V | Missense | 1 |
| COAD | Colon adenocarcinoma | I140I | Silent | 1 |
| COAD | Colon adenocarcinoma | M247T | Missense | 1 |
| COAD | Colon adenocarcinoma | M360T | Missense | 1 |
| COAD | Colon adenocarcinoma | R300C | Missense | 1 |
| COAD | Colon adenocarcinoma | S289S | Silent | 1 |
| COAD | Colon adenocarcinoma | V223M | Missense | 1 |
| ESCA | Esophageal carcinoma | K15I | Missense | 1 |
| ESCA | Esophageal carcinoma | S289S | Silent | 1 |
| ESCA | Esophageal carcinoma | T24T | Silent | 1 |
| GBM | Glioblastoma multiforme | G84V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D390G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I250V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R100W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S146C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S388F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G139R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A306T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S31P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y345C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D302N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D371N | Missense | 1 |
| LUAD | Lung adenocarcinoma | A129S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A129T | Missense | 1 |
| LUAD | Lung adenocarcinoma | F311F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G356W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G380* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | I262I | Silent | 1 |
| LUAD | Lung adenocarcinoma | K154K | Silent | 1 |
| LUAD | Lung adenocarcinoma | L382L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R251W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R349Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R58W | Missense | 1 |
| LUAD | Lung adenocarcinoma | S102C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S31P | Missense | 1 |
| LUAD | Lung adenocarcinoma | T163T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V200V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V224A | Missense | 1 |
| LUAD | Lung adenocarcinoma | W239L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y193C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E150Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q337H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D369D | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | I250M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | M247R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P53P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R349Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S31P | Missense | 1 |
| READ | Rectum adenocarcinoma | A306T | Missense | 1 |
| READ | Rectum adenocarcinoma | I140I | Silent | 1 |
| READ | Rectum adenocarcinoma | M247V | Missense | 1 |
| SARC | Sarcoma | D375N | Missense | 1 |
| SARC | Sarcoma | R218R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D302N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D375N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E353K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E384K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G167D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H237Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H48Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I124I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P30S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R13K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V200M | Missense | 1 |
| STAD | Stomach adenocarcinoma | A219T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C45C | Silent | 1 |
| STAD | Stomach adenocarcinoma | C45Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | E352K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G57* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | K336K | Silent | 1 |
| STAD | Stomach adenocarcinoma | P56T | Missense | 1 |
| STAD | Stomach adenocarcinoma | R218W | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q337K | Missense | 1 |
| THCA | Thyroid carcinoma | Q32P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A132T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H237Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K232N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L382M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R13M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R251W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T338T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V200V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V253M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 8.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 4.5 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 18.2 | 11.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 9.1 | 1.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 5.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 27.3 | 12.9 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 4.5 | 2.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.5 | 9.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 4.5 | 2.4 | 0 |
| SARC | Sarcoma | 247 | 4.5 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 4.5 | 11.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.1 | 5.9 | 50 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 3.5 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 8.2 | 0 |