Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R616H | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D85Y | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E268Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F134F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L50L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P550A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q30Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q507E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q571H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V149V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E521E | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q694* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | Q833* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S522C | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y123D | Missense | 1 |
| CESC | Cervical and endocervical cancers | R719H | Missense | 1 |
| CESC | Cervical and endocervical cancers | S2S | Silent | 1 |
| CESC | Cervical and endocervical cancers | V203M | Missense | 1 |
| COAD | Colon adenocarcinoma | A625T | Missense | 1 |
| COAD | Colon adenocarcinoma | D662D | Silent | 1 |
| COAD | Colon adenocarcinoma | E402* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E631* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G189E | Missense | 1 |
| COAD | Colon adenocarcinoma | I397I | Silent | 1 |
| COAD | Colon adenocarcinoma | I400T | Missense | 1 |
| COAD | Colon adenocarcinoma | L157L | Silent | 1 |
| COAD | Colon adenocarcinoma | L157P | Missense | 1 |
| COAD | Colon adenocarcinoma | M698L | Missense | 1 |
| COAD | Colon adenocarcinoma | R143H | Missense | 1 |
| COAD | Colon adenocarcinoma | R27R | Silent | 1 |
| COAD | Colon adenocarcinoma | T763I | Missense | 1 |
| COAD | Colon adenocarcinoma | V219V | Silent | 1 |
| COAD | Colon adenocarcinoma | W274* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | A227T | Missense | 1 |
| ESCA | Esophageal carcinoma | G570A | Missense | 1 |
| GBM | Glioblastoma multiforme | C290F | Missense | 1 |
| GBM | Glioblastoma multiforme | S250F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S501I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V814I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D258N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M454T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P246P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P392P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | Q39* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | E796E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G825G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L800S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D118Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | D512V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G825G | Silent | 1 |
| LUAD | Lung adenocarcinoma | I327I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L96L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R314G | Missense | 1 |
| LUAD | Lung adenocarcinoma | S425R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E369Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E631Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R10L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S807C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L157L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | H534P | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | V575I | Missense | 1 |
| READ | Rectum adenocarcinoma | E796* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | F141C | Missense | 1 |
| READ | Rectum adenocarcinoma | L157I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D78N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S178F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S681P | Missense | 1 |
| STAD | Stomach adenocarcinoma | F335L | Missense | 1 |
| STAD | Stomach adenocarcinoma | G108E | Missense | 1 |
| STAD | Stomach adenocarcinoma | G536C | Missense | 1 |
| STAD | Stomach adenocarcinoma | I165F | Missense | 1 |
| STAD | Stomach adenocarcinoma | R143H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S623F | Missense | 1 |
| THCA | Thyroid carcinoma | I395F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E139D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E240D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E264* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N223T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R359Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R719R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S287I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S509I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 20 | 7.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5 | 3.6 | 25 |
| CESC | Cervical and endocervical cancers | 194 | 5 | 3.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 25 | 16.1 | 37.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.6 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 3.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 10 | 3.6 | 12.5 |
| LIHC | Liver hepatocellular carcinoma | 373 | 10 | 1.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15 | 7.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 7.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 5 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.8 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.6 | 12.5 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 5.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5 | 14.3 | 12.5 |