Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | A297T | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C373F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E111K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E125* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E125K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E213* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E285K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E395Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E431K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E469D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L10L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R314* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R351Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S475* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S93* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | Q295E | Missense | 1 |
| BRCA | Breast invasive carcinoma | S382L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V133V | Silent | 1 |
| BRCA | Breast invasive carcinoma | W82C | Missense | 1 |
| CESC | Cervical and endocervical cancers | P88S | Missense | 1 |
| CESC | Cervical and endocervical cancers | R151K | Missense | 1 |
| COAD | Colon adenocarcinoma | A162V | Missense | 1 |
| COAD | Colon adenocarcinoma | D525E | Missense | 1 |
| COAD | Colon adenocarcinoma | N493N | Silent | 1 |
| COAD | Colon adenocarcinoma | P29H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q438Q | Silent | 1 |
| COAD | Colon adenocarcinoma | S443Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D26H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E395K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I139T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L400L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L440L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M418K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R299T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R517T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H298Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R182* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | K317Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K338* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E310A | Missense | 1 |
| LUAD | Lung adenocarcinoma | I403M | Missense | 1 |
| LUAD | Lung adenocarcinoma | L383L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L444V | Missense | 1 |
| LUAD | Lung adenocarcinoma | P41P | Silent | 1 |
| LUAD | Lung adenocarcinoma | S102* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S118* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S475* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | G480V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R404P | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R404G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P197S | Missense | 1 |
| READ | Rectum adenocarcinoma | R354R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A445A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D349N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G148G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K364R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R314* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | K220R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L419W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R316C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R404W | Missense | 1 |
| THCA | Thyroid carcinoma | K220R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D121Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D274N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E498D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F77C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G221G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I397S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K70Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N38H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N493K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q321K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R292M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R314* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R351Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.3 | 15.4 | 41.7 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 5.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.7 | 7.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 16.7 | 11.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 8.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.9 | 8.3 |
| LUAD | Lung adenocarcinoma | 533 | 16.7 | 5.8 | 25 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 8.3 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.7 | 3.8 | 8.3 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 7.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.9 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.3 | 25 | 8.3 |