Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | F212V | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E385Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L91V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P35S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R40H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S335L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y122* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Y95C | Missense | 1 |
| BRCA | Breast invasive carcinoma | G97D | Missense | 1 |
| BRCA | Breast invasive carcinoma | H328P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S123L | Missense | 1 |
| CESC | Cervical and endocervical cancers | A68D | Missense | 1 |
| COAD | Colon adenocarcinoma | E349K | Missense | 1 |
| COAD | Colon adenocarcinoma | G26G | Silent | 1 |
| COAD | Colon adenocarcinoma | K399T | Missense | 1 |
| COAD | Colon adenocarcinoma | N219K | Missense | 1 |
| COAD | Colon adenocarcinoma | N275S | Missense | 1 |
| COAD | Colon adenocarcinoma | P180S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q167H | Missense | 1 |
| COAD | Colon adenocarcinoma | R308* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R40H | Missense | 1 |
| COAD | Colon adenocarcinoma | R40S | Missense | 1 |
| COAD | Colon adenocarcinoma | S15L | Missense | 1 |
| ESCA | Esophageal carcinoma | D74E | Missense | 1 |
| ESCA | Esophageal carcinoma | P198T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A388A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I271T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P130Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q304* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R331C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V195D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G21E | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N163N | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P35P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q194K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S6T | Missense | 1 |
| LUAD | Lung adenocarcinoma | P93S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A378D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F222F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T394T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V169V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R40C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A397T | Missense | 1 |
| READ | Rectum adenocarcinoma | D74G | Missense | 1 |
| READ | Rectum adenocarcinoma | N43N | Silent | 1 |
| SARC | Sarcoma | G100S | Missense | 1 |
| SARC | Sarcoma | N351N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F184F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G94S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P111S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P224L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P237L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P339A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P342S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P47L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S221F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S289L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S335L | Missense | 1 |
| STAD | Stomach adenocarcinoma | D19D | Silent | 1 |
| STAD | Stomach adenocarcinoma | P135S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P215L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R40C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S335S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S34N | Missense | 1 |
| THCA | Thyroid carcinoma | H144Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A294A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E408* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G29D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G333G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K12* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P206H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P215P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R369W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R405C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S218Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S335S | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 10.7 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.2 | 16.1 | 20 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.6 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 7.1 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 12.5 | 1.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 1.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 18.8 | 1.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.2 | 1.8 | 0 |
| SARC | Sarcoma | 247 | 6.2 | 1.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.2 | 17.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 7.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 25 | 12.5 | 40 |