Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R52Q | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | D296N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D514N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E184Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E210Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I272V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L100L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L109L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L55F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q90E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R13K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S79L | Missense | 1 |
| BRCA | Breast invasive carcinoma | H708Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | M442T | Missense | 1 |
| BRCA | Breast invasive carcinoma | T546T | Silent | 1 |
| CESC | Cervical and endocervical cancers | E16K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L55F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S274C | Missense | 1 |
| COAD | Colon adenocarcinoma | D21G | Missense | 1 |
| COAD | Colon adenocarcinoma | G186D | Missense | 1 |
| COAD | Colon adenocarcinoma | I631V | Missense | 1 |
| COAD | Colon adenocarcinoma | P418P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q131Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q310R | Missense | 1 |
| COAD | Colon adenocarcinoma | R319W | Missense | 1 |
| COAD | Colon adenocarcinoma | R511R | Silent | 1 |
| COAD | Colon adenocarcinoma | R52W | Missense | 1 |
| COAD | Colon adenocarcinoma | R75Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S19P | Missense | 1 |
| ESCA | Esophageal carcinoma | T308T | Silent | 1 |
| GBM | Glioblastoma multiforme | R154W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F163F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F353L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N228S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P269T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S512N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V541V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P15H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q721Q | Silent | 1 |
| LGG | Brain Lower Grade Glioma | I387V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M590I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P433S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R534H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D366V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G236A | Missense | 1 |
| LUAD | Lung adenocarcinoma | K12N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L126L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P483T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q286Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R202P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R609R | Silent | 1 |
| LUAD | Lung adenocarcinoma | V216E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R395G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | N707D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P269S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R319Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R52Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A264S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | I731I | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L518L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R154W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R511H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S19A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S304Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A264T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R380W | Missense | 1 |
| SARC | Sarcoma | E660D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F163F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F336F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L384L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R320R | Silent | 1 |
| STAD | Stomach adenocarcinoma | E491K | Missense | 1 |
| STAD | Stomach adenocarcinoma | M570V | Missense | 1 |
| STAD | Stomach adenocarcinoma | R202R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R365Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T190M | Missense | 1 |
| THYM | Thymoma | L200R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K425K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L234L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L580P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R609* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R75Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S127S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V734I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.7 | 14.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 4.3 | 3.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13 | 17.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 4.3 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.7 | 6.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.3 | 1.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13 | 9.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 6.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 8.7 | 8.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 17.4 | 0 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 4.3 | 6.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 1.6 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 13 | 4.8 | 100 |