Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | C385C | Silent | 4 |
| SKCM | Skin Cutaneous Melanoma | G149G | Silent | 3 |
| SKCM | Skin Cutaneous Melanoma | E293K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | G323E | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | H207Y | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | M502I | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R159C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E412K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E483E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E87Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G373G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L348F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S504S | Silent | 1 |
| BRCA | Breast invasive carcinoma | R73C | Missense | 1 |
| BRCA | Breast invasive carcinoma | T361I | Missense | 1 |
| CESC | Cervical and endocervical cancers | L348F | Missense | 1 |
| COAD | Colon adenocarcinoma | F343L | Missense | 1 |
| COAD | Colon adenocarcinoma | L197F | Missense | 1 |
| COAD | Colon adenocarcinoma | L69P | Missense | 1 |
| COAD | Colon adenocarcinoma | S111Y | Missense | 1 |
| ESCA | Esophageal carcinoma | S141S | Silent | 1 |
| ESCA | Esophageal carcinoma | V8V | Silent | 1 |
| GBM | Glioblastoma multiforme | L461M | Missense | 1 |
| GBM | Glioblastoma multiforme | Q90E | Missense | 1 |
| GBM | Glioblastoma multiforme | V274F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E404K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I112V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K508N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R123H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R73H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T515P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y344Y | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | C385Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V258V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G275S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T77T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P491P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | C420* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | E412V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I216F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N268N | Silent | 1 |
| LUAD | Lung adenocarcinoma | A231A | Silent | 1 |
| LUAD | Lung adenocarcinoma | G395V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I256I | Silent | 1 |
| LUAD | Lung adenocarcinoma | I289F | Missense | 1 |
| LUAD | Lung adenocarcinoma | K315K | Silent | 1 |
| LUAD | Lung adenocarcinoma | N295K | Missense | 1 |
| LUAD | Lung adenocarcinoma | N364K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P241T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q278* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R137I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R486I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R524W | Missense | 1 |
| LUAD | Lung adenocarcinoma | V338F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A388G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D49H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E480Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G96W | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | C385R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R123R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S164S | Silent | 1 |
| SARC | Sarcoma | S63S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | C420C | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D374N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D424V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D426D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E298K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G149E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G221R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G95E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G96G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K518K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L488P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N321S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P491S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q201* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S314C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S447F | Missense | 1 |
| STAD | Stomach adenocarcinoma | D334E | Missense | 1 |
| STAD | Stomach adenocarcinoma | E412G | Missense | 1 |
| STAD | Stomach adenocarcinoma | K51K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L179M | Missense | 1 |
| STAD | Stomach adenocarcinoma | N281H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S368L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A388E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A388V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C350Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E412D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F271C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F345L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F399C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I290I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K150R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K508K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L155I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L197I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T121N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T436S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V113V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.7 | 4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.9 | 5.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.5 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.2 | 8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.2 | 1.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.2 | 1.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 2.7 | 33.3 |
| LUAD | Lung adenocarcinoma | 533 | 9.7 | 12 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 5.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.5 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 3.2 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 22.6 | 25.3 | 33.3 |
| STAD | Stomach adenocarcinoma | 393 | 3.2 | 6.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.7 | 18.7 | 0 |