Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | L1341L | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | Q278H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | S498* | Nonsense | 2 |
| PRAD | Prostate adenocarcinoma | Q278H | Missense | 2 |
| STAD | Stomach adenocarcinoma | A657V | Missense | 2 |
| STAD | Stomach adenocarcinoma | R596W | Missense | 2 |
| TGCT | Testicular Germ Cell Tumors | Q281Q | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D1758N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E115K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E923* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | H476Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1357V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1702L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M949I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1389Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S1013C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1306C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1420C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1508F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1550C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1550F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1551L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1616F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1630C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S3C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S489* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S565P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S67C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V1240V | Silent | 1 |
| BRCA | Breast invasive carcinoma | A75A | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q479* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | T723A | Missense | 1 |
| CESC | Cervical and endocervical cancers | E830K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E869Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E943Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | L201V | Missense | 1 |
| COAD | Colon adenocarcinoma | A403T | Missense | 1 |
| COAD | Colon adenocarcinoma | A601T | Missense | 1 |
| COAD | Colon adenocarcinoma | C1583R | Missense | 1 |
| COAD | Colon adenocarcinoma | D1569D | Silent | 1 |
| COAD | Colon adenocarcinoma | G90A | Missense | 1 |
| COAD | Colon adenocarcinoma | M393I | Missense | 1 |
| COAD | Colon adenocarcinoma | P1295T | Missense | 1 |
| COAD | Colon adenocarcinoma | P394S | Missense | 1 |
| COAD | Colon adenocarcinoma | R1046R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1058H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1147W | Missense | 1 |
| COAD | Colon adenocarcinoma | R26H | Missense | 1 |
| COAD | Colon adenocarcinoma | S482R | Missense | 1 |
| COAD | Colon adenocarcinoma | T1484K | Missense | 1 |
| COAD | Colon adenocarcinoma | T302P | Missense | 1 |
| ESCA | Esophageal carcinoma | D1800N | Missense | 1 |
| ESCA | Esophageal carcinoma | F1270S | Missense | 1 |
| ESCA | Esophageal carcinoma | Q281Q | Silent | 1 |
| ESCA | Esophageal carcinoma | R1307R | Silent | 1 |
| GBM | Glioblastoma multiforme | A309T | Missense | 1 |
| GBM | Glioblastoma multiforme | G520S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A741A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C481F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H313Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1219L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L468L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P109S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1576H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1215S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1641S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1733S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T221I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1192G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V151M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A1819T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A327S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G817V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K1714* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K978M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q278H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q281Q | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q812H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1571T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A233G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A589V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D582N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E830K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G206G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G995D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A411S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K1317R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L1540L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q888L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S170S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A657S | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1292L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L579V | Missense | 1 |
| LUAD | Lung adenocarcinoma | P730P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1691K | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q573* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R1161R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1226S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1733S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T1669T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T436R | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y1878N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E60Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1172L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1466R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S1733L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T379S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V818L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G1388R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P95L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1600W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S1338S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | W914* | Nonsense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | L1239R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1631T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | C728R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D969D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R7G | Missense | 1 |
| READ | Rectum adenocarcinoma | D582A | Missense | 1 |
| SARC | Sarcoma | V1835V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1507A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1507S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C1860* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1028K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1737E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E943E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E990E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F1310F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F1424F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F370L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1166G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1767G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1304L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L308L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L612L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L927L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M1849R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1169L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1193S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1567P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1653S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1757S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P217S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P331L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P371S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P705L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P798S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P917L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1311* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1632F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1443V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A970T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D562D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E764* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | F1344I | Missense | 1 |
| STAD | Stomach adenocarcinoma | G613W | Missense | 1 |
| STAD | Stomach adenocarcinoma | G677C | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1303* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | K802N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L686V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1298P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1432T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1477S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P340S | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q211R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q35L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1058H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1142H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1167Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1544Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1121G | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1133S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1681G | Missense | 1 |
| STAD | Stomach adenocarcinoma | S740S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T1150T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T1426T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V1599V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V542A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A1694S | Missense | 1 |
| THCA | Thyroid carcinoma | R5* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1331V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1746V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A734T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1171C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C918R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1800N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1264E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F1344F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1840R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G380R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M1413V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1142C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R167Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1724W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R536H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R994W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1637S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S361S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S880N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1189V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.6 | 14 | 30.8 |
| BRCA | Breast invasive carcinoma | 976 | 1.7 | 0.7 | 7.7 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 3.4 | 9.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.4 | 1.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10.3 | 3.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.7 | 4.4 | 7.7 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.7 | 4.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.4 | 2.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 10.3 | 3.7 | 7.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 1.7 | 3.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.7 | 2.2 | 7.7 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.7 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.7 | 3.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0.7 | 0 |
| SARC | Sarcoma | 247 | 1.7 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 22.4 | 11 | 15.4 |
| STAD | Stomach adenocarcinoma | 393 | 12.1 | 16.9 | 15.4 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.4 | 0.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 7.7 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.3 | 10.3 | 0 |