Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | P418P | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E338* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | E238Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H291Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L185V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q183E | Missense | 1 |
| BRCA | Breast invasive carcinoma | G163R | Missense | 1 |
| BRCA | Breast invasive carcinoma | T168M | Missense | 1 |
| BRCA | Breast invasive carcinoma | W254* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | D410D | Silent | 1 |
| COAD | Colon adenocarcinoma | D99N | Missense | 1 |
| COAD | Colon adenocarcinoma | N414H | Missense | 1 |
| COAD | Colon adenocarcinoma | P501P | Silent | 1 |
| COAD | Colon adenocarcinoma | R47Q | Missense | 1 |
| COAD | Colon adenocarcinoma | V520L | Missense | 1 |
| ESCA | Esophageal carcinoma | E363D | Missense | 1 |
| ESCA | Esophageal carcinoma | T217K | Missense | 1 |
| GBM | Glioblastoma multiforme | P420S | Missense | 1 |
| GBM | Glioblastoma multiforme | S441L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H291Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L290L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R161K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L21F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P253Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V343A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G417S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T31I | Missense | 1 |
| LUAD | Lung adenocarcinoma | E435* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | F189F | Silent | 1 |
| LUAD | Lung adenocarcinoma | P447S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P527P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | I309F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I309I | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L503L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L153F | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | F189L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A171T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A405A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I266I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P418L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R307* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S260F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S314F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A171T | Missense | 1 |
| STAD | Stomach adenocarcinoma | S396* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | T217T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V287A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | N33S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A484S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E229* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R105Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V125M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 11.4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.7 | 14.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.7 | 11.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 5.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.3 | 5.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 5.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 5.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 16.7 | 2.9 | 14.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 16.7 | 2.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 2.9 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 33.3 | 8.6 | 14.3 |
| STAD | Stomach adenocarcinoma | 393 | 8.3 | 5.7 | 14.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 8.6 | 42.9 |