Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E274K | Missense | 2 |
| COAD | Colon adenocarcinoma | F312L | Missense | 2 |
| COAD | Colon adenocarcinoma | R128C | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E123K | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E385* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E74K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E8Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H369L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q134K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V110A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V15V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E239Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E419K | Missense | 1 |
| BRCA | Breast invasive carcinoma | L30I | Missense | 1 |
| CESC | Cervical and endocervical cancers | D317N | Missense | 1 |
| COAD | Colon adenocarcinoma | A270V | Missense | 1 |
| COAD | Colon adenocarcinoma | E313K | Missense | 1 |
| COAD | Colon adenocarcinoma | F312F | Silent | 1 |
| COAD | Colon adenocarcinoma | F320V | Missense | 1 |
| COAD | Colon adenocarcinoma | N276S | Missense | 1 |
| COAD | Colon adenocarcinoma | R339S | Missense | 1 |
| COAD | Colon adenocarcinoma | R340H | Missense | 1 |
| COAD | Colon adenocarcinoma | T416M | Missense | 1 |
| COAD | Colon adenocarcinoma | V15I | Missense | 1 |
| ESCA | Esophageal carcinoma | Q47* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D231V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E394Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L33V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N342T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q40* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S43I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W41C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | F367F | Silent | 1 |
| LGG | Brain Lower Grade Glioma | F312F | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E117G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P136P | Silent | 1 |
| LUAD | Lung adenocarcinoma | E178G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R340R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S354* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | L78L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | F312F | Silent | 1 |
| READ | Rectum adenocarcinoma | E313K | Missense | 1 |
| READ | Rectum adenocarcinoma | R340H | Missense | 1 |
| SARC | Sarcoma | D169Y | Missense | 1 |
| SARC | Sarcoma | G174R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H315Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | A270A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C277C | Silent | 1 |
| STAD | Stomach adenocarcinoma | G336D | Missense | 1 |
| STAD | Stomach adenocarcinoma | I138I | Silent | 1 |
| STAD | Stomach adenocarcinoma | L251R | Missense | 1 |
| STAD | Stomach adenocarcinoma | N26K | Missense | 1 |
| STAD | Stomach adenocarcinoma | N276H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R128C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D9Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E212* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L203L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L236P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N167K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N207N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N342H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P28L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S314Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y180C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.7 | 10 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.7 | 28 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 20 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 12 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 7.7 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.7 | 2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 2 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.7 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 7.7 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4 | 0 |
| SARC | Sarcoma | 247 | 0 | 4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 23.1 | 10 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 15.4 | 18 | 20 |