Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | K176N | Missense | 3 |
| BRCA | Breast invasive carcinoma | V636G | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P1373P | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E1102Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1168K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1173K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1173Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1328K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E562Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F250V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1559K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M959I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1424A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1528H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R38C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S211C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y268Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | D178N | Missense | 1 |
| BRCA | Breast invasive carcinoma | D705N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E561K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G683G | Silent | 1 |
| BRCA | Breast invasive carcinoma | R1491C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S32R | Missense | 1 |
| BRCA | Breast invasive carcinoma | S681P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S687R | Missense | 1 |
| BRCA | Breast invasive carcinoma | S712Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | T669R | Missense | 1 |
| BRCA | Breast invasive carcinoma | W438* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | E1173K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L279L | Silent | 1 |
| CESC | Cervical and endocervical cancers | P1339L | Missense | 1 |
| CESC | Cervical and endocervical cancers | S35* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | W438* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A1340V | Missense | 1 |
| COAD | Colon adenocarcinoma | C344Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D102D | Silent | 1 |
| COAD | Colon adenocarcinoma | G1291C | Missense | 1 |
| COAD | Colon adenocarcinoma | K1190R | Missense | 1 |
| COAD | Colon adenocarcinoma | P1498P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1194R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1196R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1200R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1216R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1300C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1349Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R205* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T72T | Silent | 1 |
| COAD | Colon adenocarcinoma | V354V | Silent | 1 |
| ESCA | Esophageal carcinoma | K1190R | Missense | 1 |
| ESCA | Esophageal carcinoma | L316Q | Missense | 1 |
| ESCA | Esophageal carcinoma | M337L | Missense | 1 |
| ESCA | Esophageal carcinoma | P1458T | Missense | 1 |
| ESCA | Esophageal carcinoma | R358W | Missense | 1 |
| ESCA | Esophageal carcinoma | T1147K | Missense | 1 |
| ESCA | Esophageal carcinoma | T658K | Missense | 1 |
| GBM | Glioblastoma multiforme | A1155V | Missense | 1 |
| GBM | Glioblastoma multiforme | D129A | Missense | 1 |
| GBM | Glioblastoma multiforme | R1172H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A770V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D662N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E31E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G169R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1283P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P935L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S723R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T977T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V471V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1192K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P1510P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R1192K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R585S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S154T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S571C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S621G | Missense | 1 |
| LAML | Acute Myeloid Leukemia | S372S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E1316E | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E524K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I715T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L1566F | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P156L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R189H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V184I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H1426Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | A457S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D351E | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1480R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1283R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P162L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R116W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R21* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S479S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S710N | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y437Y | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A1260T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D129V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E398E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1413P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1493T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R1216C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D27Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L1217F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P553L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q672* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1405C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E1301K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P548P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S1434F | Missense | 1 |
| READ | Rectum adenocarcinoma | P788P | Silent | 1 |
| SARC | Sarcoma | G243E | Missense | 1 |
| SARC | Sarcoma | G243G | Silent | 1 |
| SARC | Sarcoma | G685E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1359A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D1138D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1486K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G757E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K635K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1256L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L527L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L644F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L951L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1004L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1004P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1244S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1248L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1248P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1273S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1336S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1361P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1373L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1413L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1443L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1469S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P477P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P553S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P80L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P949S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1216C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1349W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1491C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R287H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R85C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S136S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1524P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S582W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S958F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1127T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1208V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C125R | Missense | 1 |
| STAD | Stomach adenocarcinoma | H1485H | Silent | 1 |
| STAD | Stomach adenocarcinoma | L279P | Missense | 1 |
| STAD | Stomach adenocarcinoma | M329V | Missense | 1 |
| STAD | Stomach adenocarcinoma | N603D | Missense | 1 |
| STAD | Stomach adenocarcinoma | P478P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P931P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P940L | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q410* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1146W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1196R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1216H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1261R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1302Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R588W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R691C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1298I | Missense | 1 |
| STAD | Stomach adenocarcinoma | T711A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1422M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | E499G | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L761M | Missense | 1 |
| THCA | Thyroid carcinoma | G377D | Missense | 1 |
| THCA | Thyroid carcinoma | P80L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A661V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D102D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D695N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1389K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E393K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G587V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I392V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K538I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K77N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1244P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1192K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1312W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R649H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R691C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S582S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S609G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S710N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V471I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y1293C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y330Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y374Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.1 | 10.8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2 | 7.9 | 14.3 |
| CESC | Cervical and endocervical cancers | 194 | 2 | 1.4 | 28.6 |
| COAD | Colon adenocarcinoma | 367 | 16.3 | 4.3 | 14.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.2 | 3.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2 | 3.6 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 2 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2 | 4.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.1 | 5 | 14.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.1 | 2.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.9 | 14.3 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2 | 1.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2 | 0 | 0 |
| SARC | Sarcoma | 247 | 2 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 26.5 | 16.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 10.2 | 10.8 | 14.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.4 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.2 | 11.5 | 0 |