Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | G370V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L239L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R204L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S188* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | C398Y | Missense | 1 |
| COAD | Colon adenocarcinoma | A371V | Missense | 1 |
| COAD | Colon adenocarcinoma | L18R | Missense | 1 |
| COAD | Colon adenocarcinoma | S248I | Missense | 1 |
| COAD | Colon adenocarcinoma | V74A | Missense | 1 |
| ESCA | Esophageal carcinoma | R88L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I365F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L125R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R393W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T2T | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R307Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E173G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E386G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I110S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A323A | Silent | 1 |
| LUAD | Lung adenocarcinoma | C87F | Missense | 1 |
| LUAD | Lung adenocarcinoma | G207G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G259C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q309R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S113G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A300G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V265V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | I110S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L271L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P319S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y399C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R114Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R127H | Missense | 1 |
| READ | Rectum adenocarcinoma | R123Q | Missense | 1 |
| SARC | Sarcoma | S38F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L264L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L65F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R114R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S170I | Missense | 1 |
| STAD | Stomach adenocarcinoma | E173K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G207G | Silent | 1 |
| STAD | Stomach adenocarcinoma | R40Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R95Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S190S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | K275N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A300T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A339A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R78R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R95Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S352N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T167T | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.7 | 5.6 | 100 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 11.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 8.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 5.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15.4 | 11.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.7 | 2.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 7.7 | 5.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 5.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 5.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 15.4 | 8.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 23.1 | 8.3 | 0 |