Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | S250G | Missense | 4 |
| SKCM | Skin Cutaneous Melanoma | R844* | Nonsense | 3 |
| BLCA | Bladder urothelial carcinoma | A1417G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1140N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D793N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1344Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1389K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E341K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E347K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E470Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E521Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E586Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E754Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E808K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1165N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1383F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S475F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S874L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y472Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | G1316A | Missense | 1 |
| BRCA | Breast invasive carcinoma | K663N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L925L | Silent | 1 |
| CESC | Cervical and endocervical cancers | D477N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E97Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | S1267* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | D1173D | Silent | 1 |
| COAD | Colon adenocarcinoma | E808D | Missense | 1 |
| COAD | Colon adenocarcinoma | G18D | Missense | 1 |
| COAD | Colon adenocarcinoma | I351I | Silent | 1 |
| COAD | Colon adenocarcinoma | I733I | Silent | 1 |
| COAD | Colon adenocarcinoma | K587R | Missense | 1 |
| COAD | Colon adenocarcinoma | K996N | Missense | 1 |
| COAD | Colon adenocarcinoma | L943F | Missense | 1 |
| COAD | Colon adenocarcinoma | R1059C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1084* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1150* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1208R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1231* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1269W | Missense | 1 |
| COAD | Colon adenocarcinoma | R578H | Missense | 1 |
| COAD | Colon adenocarcinoma | R844* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T201T | Silent | 1 |
| COAD | Colon adenocarcinoma | T668T | Silent | 1 |
| ESCA | Esophageal carcinoma | K1228K | Silent | 1 |
| ESCA | Esophageal carcinoma | P1155S | Missense | 1 |
| GBM | Glioblastoma multiforme | N269S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A380A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D145N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D599D | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E965* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G438G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I634M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1256K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1133P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R728M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1332* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S719L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S832A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1435V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | C638* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E538D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1328R | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S689Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D261N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E1250* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | K1075E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q1116R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R174K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T539T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D889Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E863K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M260V | Missense | 1 |
| LUAD | Lung adenocarcinoma | E347* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | I1034V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I1384S | Missense | 1 |
| LUAD | Lung adenocarcinoma | K751I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q729Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1048Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1276* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | C938F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D1142G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F595L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P607P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V664V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | D1367G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L126L | Silent | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | Q1116Q | Silent | 1 |
| PRAD | Prostate adenocarcinoma | E608Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K645N | Missense | 1 |
| READ | Rectum adenocarcinoma | D1173N | Missense | 1 |
| READ | Rectum adenocarcinoma | R1090* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R1272* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | V771A | Missense | 1 |
| SARC | Sarcoma | A1402T | Missense | 1 |
| SARC | Sarcoma | R1272* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | A964A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E417K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E538K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E720K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F455Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H436H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K468K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L161F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L161L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L823L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1297C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R195* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R800* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R922C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1053F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1064S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1226S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S882R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T668I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W102* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A1314T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1402E | Missense | 1 |
| STAD | Stomach adenocarcinoma | E715* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | E804K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1043G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G1047G | Silent | 1 |
| STAD | Stomach adenocarcinoma | N901T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1133L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1146C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1146H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1204* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S492Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | S652N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T3A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T482P | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | D132H | Missense | 1 |
| THCA | Thyroid carcinoma | C912C | Silent | 1 |
| THCA | Thyroid carcinoma | D477G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1279Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D184Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D549Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1381E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E536D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G160D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G484E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I1052I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I209I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L943L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1088H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1163Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1231Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1269W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1274W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R851H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S862N | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.8 | 16.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.8 | 2.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.1 | 4.5 |
| COAD | Colon adenocarcinoma | 367 | 16.7 | 12.4 | 18.2 |
| ESCA | Esophageal carcinoma | 185 | 2.8 | 1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 16.7 | 5.2 | 9.1 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.8 | 1 | 4.5 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.8 | 4.1 | 4.5 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 2.8 | 4.1 | 9.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 5.6 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.8 | 1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 2.8 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.1 | 9.1 |
| SARC | Sarcoma | 247 | 0 | 1 | 4.5 |
| SKCM | Skin Cutaneous Melanoma | 290 | 19.4 | 10.3 | 27.3 |
| STAD | Stomach adenocarcinoma | 393 | 5.6 | 11.3 | 9.1 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1 | 0 |
| THCA | Thyroid carcinoma | 495 | 2.8 | 1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.1 | 13.4 | 0 |