Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A133V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I621I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L435L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L585L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R205Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S391C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T188S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E267K | Missense | 1 |
| BRCA | Breast invasive carcinoma | H164H | Silent | 1 |
| BRCA | Breast invasive carcinoma | L475L | Silent | 1 |
| BRCA | Breast invasive carcinoma | M561V | Missense | 1 |
| BRCA | Breast invasive carcinoma | N568H | Missense | 1 |
| BRCA | Breast invasive carcinoma | S290F | Missense | 1 |
| BRCA | Breast invasive carcinoma | V44V | Silent | 1 |
| CESC | Cervical and endocervical cancers | R603Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | S541A | Missense | 1 |
| COAD | Colon adenocarcinoma | G370G | Silent | 1 |
| COAD | Colon adenocarcinoma | I402I | Silent | 1 |
| COAD | Colon adenocarcinoma | L627L | Silent | 1 |
| COAD | Colon adenocarcinoma | R389C | Missense | 1 |
| COAD | Colon adenocarcinoma | R603Q | Missense | 1 |
| GBM | Glioblastoma multiforme | H372H | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A405V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G386E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K286K | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | D100N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N180K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H526H | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R205* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | S161S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | V440I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G623V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M62L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Y210H | Missense | 1 |
| LUAD | Lung adenocarcinoma | F47L | Missense | 1 |
| LUAD | Lung adenocarcinoma | I20F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P181S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P242R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G203R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H484R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R544C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S502F | Missense | 1 |
| READ | Rectum adenocarcinoma | F214F | Silent | 1 |
| READ | Rectum adenocarcinoma | P302H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D100G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F58L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K647T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L615L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P160S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P181L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P221L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P516L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P516S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S297S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A133V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A405T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A542V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C454G | Missense | 1 |
| STAD | Stomach adenocarcinoma | P337P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P69H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R281W | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | S425* | Nonsense | 1 |
| THCA | Thyroid carcinoma | H372P | Missense | 1 |
| THCA | Thyroid carcinoma | R130R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A613V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D338D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I621I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K656R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N556N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R213C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R87H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T476I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V595V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y362C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 13.6 | 8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 13.6 | 8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13.6 | 4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 4.5 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.5 | 4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 4.5 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.5 | 2 | 50 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 4.5 | 2 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.1 | 16 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 4.5 | 12 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 50 |
| THCA | Thyroid carcinoma | 495 | 4.5 | 2 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.2 | 12 | 0 |