Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BRCA | Breast invasive carcinoma | W229G | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D337N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G234G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K161N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L668L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q54* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S255F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S426C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S49* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T491S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V110V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V322V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D344G | Missense | 1 |
| BRCA | Breast invasive carcinoma | I86V | Missense | 1 |
| BRCA | Breast invasive carcinoma | P557L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V388G | Missense | 1 |
| CESC | Cervical and endocervical cancers | R307S | Missense | 1 |
| COAD | Colon adenocarcinoma | G365V | Missense | 1 |
| COAD | Colon adenocarcinoma | G419E | Missense | 1 |
| COAD | Colon adenocarcinoma | G43E | Missense | 1 |
| COAD | Colon adenocarcinoma | G531G | Silent | 1 |
| COAD | Colon adenocarcinoma | P59P | Silent | 1 |
| COAD | Colon adenocarcinoma | R103I | Missense | 1 |
| COAD | Colon adenocarcinoma | R375K | Missense | 1 |
| COAD | Colon adenocarcinoma | R471M | Missense | 1 |
| COAD | Colon adenocarcinoma | R498L | Missense | 1 |
| COAD | Colon adenocarcinoma | R656R | Silent | 1 |
| COAD | Colon adenocarcinoma | T148T | Silent | 1 |
| COAD | Colon adenocarcinoma | T503P | Missense | 1 |
| COAD | Colon adenocarcinoma | T643I | Missense | 1 |
| ESCA | Esophageal carcinoma | L462F | Missense | 1 |
| ESCA | Esophageal carcinoma | Y554* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | H454Y | Missense | 1 |
| GBM | Glioblastoma multiforme | P628H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D207N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L275S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P306Q | Missense | 1 |
| LAML | Acute Myeloid Leukemia | A47S | Missense | 1 |
| LAML | Acute Myeloid Leukemia | D588D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A529V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V359I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H364H | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q279E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E488Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G348A | Missense | 1 |
| LUAD | Lung adenocarcinoma | G348V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G368G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G649D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G649G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G90R | Missense | 1 |
| LUAD | Lung adenocarcinoma | H454Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | H596L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L585Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | P295L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P385P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P415A | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q435H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R103S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S670I | Missense | 1 |
| LUAD | Lung adenocarcinoma | T326A | Missense | 1 |
| LUAD | Lung adenocarcinoma | V174V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A260E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C688F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D214H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L549L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L665L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P295A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S541S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P438L | Missense | 1 |
| READ | Rectum adenocarcinoma | K13* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R575* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | D32N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D572N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D627A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F666F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G552E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G697E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I376I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L159I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L514L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L654L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N185N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P165L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P557S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R297R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S333L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V110V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V280V | Silent | 1 |
| STAD | Stomach adenocarcinoma | D481H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R338C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T4P | Missense | 1 |
| STAD | Stomach adenocarcinoma | V577A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V614V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A47D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E525E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E538D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G579D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K147N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K161N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K592K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K626N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M143V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P142P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P387T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P617H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S327Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T84M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V569F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 13.8 | 6.7 | 40 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13.8 | 12 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.3 | 20 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 3.4 | 1.3 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.4 | 1.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.8 | 18.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.9 | 5.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.4 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 40 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 27.6 | 12 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 3.4 | 5.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.3 | 16 | 0 |