Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LIHC | Liver hepatocellular carcinoma | R668L | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S310F | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S381F | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A702T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1438Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E831K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F142F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K1665K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1108L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L200L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q10Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R689G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1023S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S341F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S349L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T1262N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V764V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | W1580L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y726Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | E416K | Missense | 1 |
| BRCA | Breast invasive carcinoma | F263F | Silent | 1 |
| BRCA | Breast invasive carcinoma | H128P | Missense | 1 |
| BRCA | Breast invasive carcinoma | I23I | Silent | 1 |
| BRCA | Breast invasive carcinoma | P650P | Silent | 1 |
| BRCA | Breast invasive carcinoma | P651A | Missense | 1 |
| BRCA | Breast invasive carcinoma | S418S | Silent | 1 |
| CESC | Cervical and endocervical cancers | I1502I | Silent | 1 |
| CESC | Cervical and endocervical cancers | L1019L | Silent | 1 |
| COAD | Colon adenocarcinoma | A1215T | Missense | 1 |
| COAD | Colon adenocarcinoma | A1607T | Missense | 1 |
| COAD | Colon adenocarcinoma | A323T | Missense | 1 |
| COAD | Colon adenocarcinoma | D1458Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D981D | Silent | 1 |
| COAD | Colon adenocarcinoma | P1179P | Silent | 1 |
| COAD | Colon adenocarcinoma | P1192P | Silent | 1 |
| COAD | Colon adenocarcinoma | P654L | Missense | 1 |
| COAD | Colon adenocarcinoma | Q683H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1132C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1150H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1487Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R812L | Missense | 1 |
| COAD | Colon adenocarcinoma | S1013S | Silent | 1 |
| COAD | Colon adenocarcinoma | S1047S | Silent | 1 |
| COAD | Colon adenocarcinoma | S267S | Silent | 1 |
| COAD | Colon adenocarcinoma | V234M | Missense | 1 |
| COAD | Colon adenocarcinoma | V764I | Missense | 1 |
| COAD | Colon adenocarcinoma | V764L | Missense | 1 |
| ESCA | Esophageal carcinoma | A1254V | Missense | 1 |
| ESCA | Esophageal carcinoma | R299W | Missense | 1 |
| ESCA | Esophageal carcinoma | S1053E | Missense | 1 |
| ESCA | Esophageal carcinoma | S479C | Missense | 1 |
| GBM | Glioblastoma multiforme | G235D | Missense | 1 |
| GBM | Glioblastoma multiforme | G441G | Silent | 1 |
| GBM | Glioblastoma multiforme | G44E | Missense | 1 |
| GBM | Glioblastoma multiforme | P644R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A906A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1174* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1278Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E454K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E558K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E664K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E985E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1025G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1637T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1408L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P773P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q191R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R689W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S207S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y305N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A725A | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1288S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S408Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V1092M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | W17R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E390D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P729P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E529G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G592S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q844Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R1201W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1043S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A702A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1244D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1287Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G708V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G766* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | K203* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | K203N | Missense | 1 |
| LUAD | Lung adenocarcinoma | M1424I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1147P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P1186L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1331L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P638T | Missense | 1 |
| LUAD | Lung adenocarcinoma | R219L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R253L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R745L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S357S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S464F | Missense | 1 |
| LUAD | Lung adenocarcinoma | T1088T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T1309T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T274K | Missense | 1 |
| LUAD | Lung adenocarcinoma | V152V | Silent | 1 |
| LUAD | Lung adenocarcinoma | W1465C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y1499C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y1500N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F680F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G1267E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H1295Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P272S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P914L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q423L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1613H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R956C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T1309T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V39M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A225G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D1677H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D581D | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E1059G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E1067* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1154A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V1094V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | Y1415* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | C577S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R913H | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A1119S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1414T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R115H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1542L | Missense | 1 |
| READ | Rectum adenocarcinoma | E1110K | Missense | 1 |
| READ | Rectum adenocarcinoma | N1461N | Silent | 1 |
| SARC | Sarcoma | E478E | Silent | 1 |
| SARC | Sarcoma | K868K | Silent | 1 |
| SARC | Sarcoma | S470F | Missense | 1 |
| SARC | Sarcoma | S762F | Missense | 1 |
| SARC | Sarcoma | S762S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A316S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A701V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D987E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G136G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G674A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G675R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L155L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M797K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1104L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1137L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1156S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1486P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P428S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P435S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P610L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P610S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P651S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q695H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R311C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R360C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R404R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1015F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1044F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1047S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1705S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S349L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S504F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S75F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S862S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V1003L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1215T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1346V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A328T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A329T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1591D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1000D | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1026K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E416E | Silent | 1 |
| STAD | Stomach adenocarcinoma | G708S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1179P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1182R | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1317P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P392T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P462Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | P642P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q358E | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1288H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1444W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1542Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R311H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R360H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R461H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1043S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1047S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1283S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S347S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S69S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Y1597Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Y180Y | Silent | 1 |
| THCA | Thyroid carcinoma | N1461S | Missense | 1 |
| THCA | Thyroid carcinoma | P13R | Missense | 1 |
| THYM | Thymoma | C114F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1254V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A368A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D307Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D73Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E474G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E664E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E775K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G537V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G708A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1559R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1696L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P642L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P654P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P786P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R176Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S352S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S679P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1676M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.6 | 5.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.8 | 2.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.9 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 8.7 | 8.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 1.4 | 2.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.2 | 6.2 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.4 | 0.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.4 | 0.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.9 | 3.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.7 | 11 | 40 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.9 | 5.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.9 | 2.7 | 40 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.7 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.4 | 0.7 | 0 |
| SARC | Sarcoma | 247 | 4.3 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 10.1 | 18.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 14.5 | 11.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.9 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.4 | 0 |
| THYM | Thymoma | 119 | 0 | 0.7 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.7 | 8.2 | 0 |