Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | P498P | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A351T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L26L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P234P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q198* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R336K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R407K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V206V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E118* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | K8N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L157M | Missense | 1 |
| BRCA | Breast invasive carcinoma | L570L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P498L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E494E | Silent | 1 |
| COAD | Colon adenocarcinoma | E374* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | K135N | Missense | 1 |
| COAD | Colon adenocarcinoma | K449E | Missense | 1 |
| COAD | Colon adenocarcinoma | N318N | Silent | 1 |
| COAD | Colon adenocarcinoma | N413I | Missense | 1 |
| COAD | Colon adenocarcinoma | P498L | Missense | 1 |
| COAD | Colon adenocarcinoma | R460C | Missense | 1 |
| COAD | Colon adenocarcinoma | R486W | Missense | 1 |
| COAD | Colon adenocarcinoma | S565S | Silent | 1 |
| COAD | Colon adenocarcinoma | W427* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R386Q | Missense | 1 |
| GBM | Glioblastoma multiforme | T428I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E397Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E58Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V123A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T14I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T19T | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E46E | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A360V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E503E | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E528K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G282S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K74N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N554N | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P498P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | A40A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K472K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T563S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G508V | Missense | 1 |
| LUAD | Lung adenocarcinoma | R265L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S344I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E291K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E504D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L570V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P259P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A581T | Missense | 1 |
| READ | Rectum adenocarcinoma | E103* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | L270M | Missense | 1 |
| SARC | Sarcoma | S565S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A483A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A86T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E394K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I323I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P259S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R460C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S170S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S414L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T280T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A354A | Silent | 1 |
| STAD | Stomach adenocarcinoma | D205A | Missense | 1 |
| STAD | Stomach adenocarcinoma | N454T | Missense | 1 |
| STAD | Stomach adenocarcinoma | R294H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R490H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S21P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S450S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S68S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A404T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A482V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E504* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E58D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L457L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N281S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q572H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R486Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T19T | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.1 | 6.4 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 3.7 | 6.4 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 3.7 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.4 | 12.8 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 6.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.7 | 2.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.7 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 11.1 | 8.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.4 | 2.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 6.4 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.7 | 6.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.1 | 16.7 |
| SARC | Sarcoma | 247 | 3.7 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 14.8 | 10.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 18.5 | 10.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.4 | 12.8 | 16.7 |