Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E200K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E813Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1045S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1085E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K698R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1057L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1132L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1169S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1392S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P489P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1363E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R308* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S1171L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1301R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S84C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S942F | Missense | 1 |
| BRCA | Breast invasive carcinoma | A733E | Missense | 1 |
| BRCA | Breast invasive carcinoma | M793V | Missense | 1 |
| BRCA | Breast invasive carcinoma | R618Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R933I | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1327C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S191C | Missense | 1 |
| CESC | Cervical and endocervical cancers | D132H | Missense | 1 |
| CESC | Cervical and endocervical cancers | D943H | Missense | 1 |
| CESC | Cervical and endocervical cancers | L104L | Silent | 1 |
| CESC | Cervical and endocervical cancers | S1133F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S1148F | Missense | 1 |
| COAD | Colon adenocarcinoma | D823Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E300E | Silent | 1 |
| COAD | Colon adenocarcinoma | E599D | Missense | 1 |
| COAD | Colon adenocarcinoma | G1024G | Silent | 1 |
| COAD | Colon adenocarcinoma | G315G | Silent | 1 |
| COAD | Colon adenocarcinoma | I350I | Silent | 1 |
| COAD | Colon adenocarcinoma | I435M | Missense | 1 |
| COAD | Colon adenocarcinoma | K246R | Missense | 1 |
| COAD | Colon adenocarcinoma | P1285T | Missense | 1 |
| COAD | Colon adenocarcinoma | Q196Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R1074Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1387W | Missense | 1 |
| COAD | Colon adenocarcinoma | R209W | Missense | 1 |
| COAD | Colon adenocarcinoma | R361* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R445Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R614R | Silent | 1 |
| COAD | Colon adenocarcinoma | R900C | Missense | 1 |
| COAD | Colon adenocarcinoma | R978Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S1327P | Missense | 1 |
| ESCA | Esophageal carcinoma | A232T | Missense | 1 |
| ESCA | Esophageal carcinoma | A918T | Missense | 1 |
| ESCA | Esophageal carcinoma | R882L | Missense | 1 |
| ESCA | Esophageal carcinoma | S760L | Missense | 1 |
| GBM | Glioblastoma multiforme | V602V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C1019* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G115R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1363* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S590P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T680A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1066V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V117G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E200D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P430P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P800T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y1414H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L1042L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N44D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E486D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G594W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S72L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S84Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E384K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P1415R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V1422V | Silent | 1 |
| LUAD | Lung adenocarcinoma | A712S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A996T | Missense | 1 |
| LUAD | Lung adenocarcinoma | G131V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1440R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G951R | Missense | 1 |
| LUAD | Lung adenocarcinoma | N408T | Missense | 1 |
| LUAD | Lung adenocarcinoma | R531R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1260S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S134T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A898T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D251N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P746L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1424L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R768L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1300F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G1024G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | M19T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q1058Q | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | S1327S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | S38N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1083D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A898V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P470S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P830P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q1268H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S760* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | D228N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E200K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G245D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P615L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q230H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R209R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R724H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R77C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S1135S | Silent | 1 |
| READ | Rectum adenocarcinoma | I265S | Missense | 1 |
| READ | Rectum adenocarcinoma | K1129T | Missense | 1 |
| READ | Rectum adenocarcinoma | S797* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | Y1239C | Missense | 1 |
| SARC | Sarcoma | L104L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | C402F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E459* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E716K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F317L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H1265N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P323L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P959S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1039C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1260F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S572L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S683L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T699T | Silent | 1 |
| STAD | Stomach adenocarcinoma | I61V | Missense | 1 |
| STAD | Stomach adenocarcinoma | L944V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P563S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P859L | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q1412R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q309* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Q581P | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1072Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R123Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1379G | Missense | 1 |
| STAD | Stomach adenocarcinoma | R531Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R933S | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1146* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | T277A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T893A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1435V | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | P800H | Missense | 1 |
| THCA | Thyroid carcinoma | A1407V | Missense | 1 |
| THCA | Thyroid carcinoma | S929R | Missense | 1 |
| THCA | Thyroid carcinoma | T252I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1407V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A869A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C93Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D463G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1219E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E456K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G79E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G951V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I576I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K184Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K187R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P82P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q196H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R302C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R441H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R882Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1119S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S353* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S829N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T552A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V376V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.3 | 11.3 | 10 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.3 | 3.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 20 | 9.7 | 10 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 3.3 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.3 | 3.2 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.3 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.3 | 0.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.3 | 1.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.7 | 5.6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 10 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.3 | 3.2 | 10 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 5.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.4 | 10 |
| SARC | Sarcoma | 247 | 3.3 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 3.3 | 8.1 | 10 |
| STAD | Stomach adenocarcinoma | 393 | 3.3 | 10.5 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2.4 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 20 | 11.3 | 10 |