Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | K669K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L343L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R135Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S513* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S628S | Silent | 1 |
| BRCA | Breast invasive carcinoma | G699G | Silent | 1 |
| BRCA | Breast invasive carcinoma | K280N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R455Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S431R | Missense | 1 |
| BRCA | Breast invasive carcinoma | S513* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | T75I | Missense | 1 |
| CESC | Cervical and endocervical cancers | E702K | Missense | 1 |
| CESC | Cervical and endocervical cancers | I345I | Silent | 1 |
| CESC | Cervical and endocervical cancers | L829L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R762C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S13F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S683F | Missense | 1 |
| COAD | Colon adenocarcinoma | A327T | Missense | 1 |
| COAD | Colon adenocarcinoma | G615S | Missense | 1 |
| COAD | Colon adenocarcinoma | I746I | Silent | 1 |
| COAD | Colon adenocarcinoma | K666T | Missense | 1 |
| COAD | Colon adenocarcinoma | N2N | Silent | 1 |
| COAD | Colon adenocarcinoma | P258S | Missense | 1 |
| COAD | Colon adenocarcinoma | P424S | Missense | 1 |
| COAD | Colon adenocarcinoma | R195H | Missense | 1 |
| COAD | Colon adenocarcinoma | R557W | Missense | 1 |
| COAD | Colon adenocarcinoma | R681R | Silent | 1 |
| COAD | Colon adenocarcinoma | T633T | Silent | 1 |
| ESCA | Esophageal carcinoma | E77E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E733Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G49* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K581N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R671Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S513* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A369S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E854* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | M15T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C570Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L414M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P651H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P348P | Silent | 1 |
| LUAD | Lung adenocarcinoma | G447V | Missense | 1 |
| LUAD | Lung adenocarcinoma | S655N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D175Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A865V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T405I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A859T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D357D | Silent | 1 |
| READ | Rectum adenocarcinoma | D94N | Missense | 1 |
| READ | Rectum adenocarcinoma | E524E | Silent | 1 |
| READ | Rectum adenocarcinoma | R595W | Missense | 1 |
| SARC | Sarcoma | Y639* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | D436D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K735R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L483L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L556F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R855S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S712S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T405T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A327A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A549T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C600C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D213E | Missense | 1 |
| STAD | Stomach adenocarcinoma | D711Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | H207H | Silent | 1 |
| STAD | Stomach adenocarcinoma | H318H | Silent | 1 |
| STAD | Stomach adenocarcinoma | H480H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K678R | Missense | 1 |
| STAD | Stomach adenocarcinoma | P144S | Missense | 1 |
| STAD | Stomach adenocarcinoma | S719S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S740F | Missense | 1 |
| STAD | Stomach adenocarcinoma | T71A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V185I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C609C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I345T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K340N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K672N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P474S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R455Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R554H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R667M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R681C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S288P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S476S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y578S | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.5 | 1.9 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 3.8 | 7.5 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 7.7 | 7.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 15.4 | 13.2 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.8 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 5.7 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.9 | 16.7 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.8 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 3.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.8 | 1.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.8 | 3.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 16.7 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 5.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 23.1 | 15.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 18.9 | 0 |