Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | P88P | Silent | 2 |
| LUAD | Lung adenocarcinoma | A713A | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | I615I | Silent | 2 |
| STAD | Stomach adenocarcinoma | R107C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D114Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D122D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D620D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F408F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F888L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I147M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I572I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K373E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K843T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P529S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R241Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R690W | Missense | 1 |
| BRCA | Breast invasive carcinoma | C653R | Missense | 1 |
| BRCA | Breast invasive carcinoma | D851G | Missense | 1 |
| BRCA | Breast invasive carcinoma | E267E | Silent | 1 |
| BRCA | Breast invasive carcinoma | H298D | Missense | 1 |
| BRCA | Breast invasive carcinoma | K843N | Missense | 1 |
| BRCA | Breast invasive carcinoma | P255P | Silent | 1 |
| BRCA | Breast invasive carcinoma | P76R | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q483H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R617W | Missense | 1 |
| CESC | Cervical and endocervical cancers | A265A | Silent | 1 |
| CESC | Cervical and endocervical cancers | L644L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R486T | Missense | 1 |
| CESC | Cervical and endocervical cancers | S6* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A320A | Silent | 1 |
| COAD | Colon adenocarcinoma | A320V | Missense | 1 |
| COAD | Colon adenocarcinoma | A708A | Silent | 1 |
| COAD | Colon adenocarcinoma | A790V | Missense | 1 |
| COAD | Colon adenocarcinoma | A890A | Silent | 1 |
| COAD | Colon adenocarcinoma | C560C | Silent | 1 |
| COAD | Colon adenocarcinoma | D455Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D682N | Missense | 1 |
| COAD | Colon adenocarcinoma | E494D | Missense | 1 |
| COAD | Colon adenocarcinoma | E598D | Missense | 1 |
| COAD | Colon adenocarcinoma | F699F | Silent | 1 |
| COAD | Colon adenocarcinoma | G43G | Silent | 1 |
| COAD | Colon adenocarcinoma | I277V | Missense | 1 |
| COAD | Colon adenocarcinoma | I881I | Silent | 1 |
| COAD | Colon adenocarcinoma | K364N | Missense | 1 |
| COAD | Colon adenocarcinoma | P182S | Missense | 1 |
| COAD | Colon adenocarcinoma | P557L | Missense | 1 |
| COAD | Colon adenocarcinoma | P861L | Missense | 1 |
| COAD | Colon adenocarcinoma | P861P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q71K | Missense | 1 |
| COAD | Colon adenocarcinoma | R107C | Missense | 1 |
| COAD | Colon adenocarcinoma | R115H | Missense | 1 |
| COAD | Colon adenocarcinoma | R400* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R627C | Missense | 1 |
| COAD | Colon adenocarcinoma | S554S | Silent | 1 |
| COAD | Colon adenocarcinoma | S683N | Missense | 1 |
| COAD | Colon adenocarcinoma | T447T | Silent | 1 |
| COAD | Colon adenocarcinoma | T731T | Silent | 1 |
| COAD | Colon adenocarcinoma | V131M | Missense | 1 |
| COAD | Colon adenocarcinoma | V430I | Missense | 1 |
| COAD | Colon adenocarcinoma | V490V | Silent | 1 |
| COAD | Colon adenocarcinoma | V561M | Missense | 1 |
| COAD | Colon adenocarcinoma | V700M | Missense | 1 |
| COAD | Colon adenocarcinoma | Y661H | Missense | 1 |
| ESCA | Esophageal carcinoma | D460D | Silent | 1 |
| ESCA | Esophageal carcinoma | R178R | Silent | 1 |
| ESCA | Esophageal carcinoma | R617W | Missense | 1 |
| ESCA | Esophageal carcinoma | S707F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A713V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C100W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D723D | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E113K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G677R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L856Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M412I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P557L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R115H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R628L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R691W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R705R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R883T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S24L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S697F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T4S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V561V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | E647A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P557P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P13S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P757P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A750V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N534S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P821L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R741Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T95T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D460G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G101G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G29E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I655I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L338L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P477P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S165K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S266T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V761A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V829M | Missense | 1 |
| LUAD | Lung adenocarcinoma | A320A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A391A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A416D | Missense | 1 |
| LUAD | Lung adenocarcinoma | D729G | Missense | 1 |
| LUAD | Lung adenocarcinoma | D729N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E2E | Silent | 1 |
| LUAD | Lung adenocarcinoma | G110S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G355G | Silent | 1 |
| LUAD | Lung adenocarcinoma | K20N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L272L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L363H | Missense | 1 |
| LUAD | Lung adenocarcinoma | L437I | Missense | 1 |
| LUAD | Lung adenocarcinoma | L5F | Missense | 1 |
| LUAD | Lung adenocarcinoma | N470D | Missense | 1 |
| LUAD | Lung adenocarcinoma | P493A | Missense | 1 |
| LUAD | Lung adenocarcinoma | R217H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R217R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S641R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S715* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | T599T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V322V | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y91N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C653F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C878S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G179L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G546E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L639L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L857L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | N544D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P143S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P88P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R610K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S405I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S72I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S733G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Y111Y | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | A55V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P557P | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | S554S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | V886L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L348M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L600L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R178* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R617W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V490V | Silent | 1 |
| PRAD | Prostate adenocarcinoma | C560C | Silent | 1 |
| READ | Rectum adenocarcinoma | F289L | Missense | 1 |
| READ | Rectum adenocarcinoma | R436W | Missense | 1 |
| READ | Rectum adenocarcinoma | S8S | Silent | 1 |
| SARC | Sarcoma | A416S | Missense | 1 |
| SARC | Sarcoma | E81K | Missense | 1 |
| SARC | Sarcoma | P395S | Missense | 1 |
| SARC | Sarcoma | V709M | Missense | 1 |
| SARC | Sarcoma | V770M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A416V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A428A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D294A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E810E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F832F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H656Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P371L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P395S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P396S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P450S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q596* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R406* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S429F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S429S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S697F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T807T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V123A | Missense | 1 |
| STAD | Stomach adenocarcinoma | A320A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A391V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D122N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E149G | Missense | 1 |
| STAD | Stomach adenocarcinoma | F513Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | G110S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G181C | Missense | 1 |
| STAD | Stomach adenocarcinoma | G189C | Missense | 1 |
| STAD | Stomach adenocarcinoma | I572M | Missense | 1 |
| STAD | Stomach adenocarcinoma | I615I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K843T | Missense | 1 |
| STAD | Stomach adenocarcinoma | M459K | Missense | 1 |
| STAD | Stomach adenocarcinoma | P200P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P674H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q853H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R296R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R400* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R547R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R704Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R779R | Silent | 1 |
| STAD | Stomach adenocarcinoma | T731T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V124L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V700M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V770M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y663H | Missense | 1 |
| THCA | Thyroid carcinoma | V501V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A170T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A320A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A391V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A689T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A750V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C626C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C653C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D30Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D336G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E584K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F699F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G23S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K263N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L639L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R115H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R116R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R219H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R296* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R400Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R436Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R580R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R691W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R704R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T95T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V288L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V93A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y889Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.1 | 5.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.5 | 4.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.5 | 0.7 | 12.5 |
| COAD | Colon adenocarcinoma | 367 | 17.7 | 14.6 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 2.5 | 1.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.8 | 9.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.3 | 0.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.3 | 0.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.3 | 2.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.1 | 4.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 12.7 | 9 | 12.5 |
| LUSC | Lung squamous cell carcinoma | 177 | 5.1 | 6.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.5 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.5 | 1.4 | 12.5 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.3 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.3 | 1.4 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.5 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 8.9 | 6.9 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 8.9 | 13.2 | 12.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 1.3 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.7 | 11.1 | 12.5 |