Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | I195I | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E198Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E198Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S268F | Missense | 1 |
| CESC | Cervical and endocervical cancers | E73K | Missense | 1 |
| COAD | Colon adenocarcinoma | H185N | Missense | 1 |
| COAD | Colon adenocarcinoma | R44Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R60C | Missense | 1 |
| COAD | Colon adenocarcinoma | S29S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T41T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R28C | Missense | 1 |
| LUAD | Lung adenocarcinoma | K136M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A6A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R165W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | F244F | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L59L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A68V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D223D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H18L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I87I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P212Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q19* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A247T | Missense | 1 |
| STAD | Stomach adenocarcinoma | H42R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R207W | Missense | 1 |
| THYM | Thymoma | R209C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D160E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G102S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P212T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R208H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 4.8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 9.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 33.3 | 14.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.1 | 0 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 4.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 11.1 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 22.2 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 22.2 | 14.3 | 100 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 14.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 4.8 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 19 | 0 |