Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D197H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E164K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E230K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E609A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G618E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H471Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q632H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y650D | Missense | 1 |
| BRCA | Breast invasive carcinoma | D481N | Missense | 1 |
| BRCA | Breast invasive carcinoma | G618R | Missense | 1 |
| CESC | Cervical and endocervical cancers | G495D | Missense | 1 |
| CESC | Cervical and endocervical cancers | S229* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A369T | Missense | 1 |
| COAD | Colon adenocarcinoma | A617V | Missense | 1 |
| COAD | Colon adenocarcinoma | R341C | Missense | 1 |
| COAD | Colon adenocarcinoma | R516Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S675N | Missense | 1 |
| COAD | Colon adenocarcinoma | Y428H | Missense | 1 |
| ESCA | Esophageal carcinoma | A281V | Missense | 1 |
| ESCA | Esophageal carcinoma | G678E | Missense | 1 |
| ESCA | Esophageal carcinoma | Y121C | Missense | 1 |
| ESCA | Esophageal carcinoma | Y497C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D557N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G195V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P447P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R424T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N346S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q190Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T517A | Missense | 1 |
| LUAD | Lung adenocarcinoma | D298H | Missense | 1 |
| LUAD | Lung adenocarcinoma | K328K | Silent | 1 |
| LUAD | Lung adenocarcinoma | L215L | Silent | 1 |
| LUAD | Lung adenocarcinoma | S549F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R282S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S159S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F273S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I347K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R649H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S673N | Missense | 1 |
| READ | Rectum adenocarcinoma | F148F | Silent | 1 |
| SARC | Sarcoma | W221* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | F329F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L493V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A168A | Silent | 1 |
| STAD | Stomach adenocarcinoma | F148F | Silent | 1 |
| STAD | Stomach adenocarcinoma | F321L | Missense | 1 |
| STAD | Stomach adenocarcinoma | G440E | Missense | 1 |
| STAD | Stomach adenocarcinoma | P447S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R199Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R516* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S669G | Missense | 1 |
| STAD | Stomach adenocarcinoma | T584T | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | V733V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A730S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E420E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E467* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E520* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F698F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P403L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R282H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R649C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 18.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.3 | 20 |
| COAD | Colon adenocarcinoma | 367 | 0 | 14 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 9.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.7 | 2.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.7 | 4.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15.4 | 4.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 7.7 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.7 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 20 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.7 | 2.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 23.1 | 11.6 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 7.7 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 15.4 | 9.3 | 40 |