Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | A133T | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | G177G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R163C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R346Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | L252L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R346W | Missense | 1 |
| CESC | Cervical and endocervical cancers | G304E | Missense | 1 |
| COAD | Colon adenocarcinoma | A358A | Silent | 1 |
| COAD | Colon adenocarcinoma | G29R | Missense | 1 |
| COAD | Colon adenocarcinoma | V196I | Missense | 1 |
| ESCA | Esophageal carcinoma | E333E | Silent | 1 |
| GBM | Glioblastoma multiforme | F235L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A2A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P388P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S366L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L341L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E203K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G236D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q13R | Missense | 1 |
| LUAD | Lung adenocarcinoma | K220N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L134I | Missense | 1 |
| LUAD | Lung adenocarcinoma | T166T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G177W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R42P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S73R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R77H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T166M | Missense | 1 |
| READ | Rectum adenocarcinoma | F190V | Missense | 1 |
| SARC | Sarcoma | I232I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F151F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F251F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R78R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T63I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T63T | Silent | 1 |
| STAD | Stomach adenocarcinoma | L134L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R69L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V196I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V360G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A186V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A32T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C195C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D317D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E203G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L341M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P128L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P140H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R153C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.2 | 6.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 6.2 | 3.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.2 | 6.2 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 3.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.2 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 9.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.2 | 6.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 9.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.1 | 0 |
| SARC | Sarcoma | 247 | 6.2 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 25 | 3.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 6.2 | 12.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 3.1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 21.9 | 0 |