Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R618C | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R716I | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E209* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | F570L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q35* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q787* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q918E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R885P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S679C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A42A | Silent | 1 |
| BRCA | Breast invasive carcinoma | E848Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G889C | Missense | 1 |
| BRCA | Breast invasive carcinoma | H462D | Missense | 1 |
| BRCA | Breast invasive carcinoma | L383L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R145C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S321Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | S440F | Missense | 1 |
| BRCA | Breast invasive carcinoma | S485R | Missense | 1 |
| CESC | Cervical and endocervical cancers | A755A | Silent | 1 |
| CESC | Cervical and endocervical cancers | R1015C | Missense | 1 |
| COAD | Colon adenocarcinoma | C906R | Missense | 1 |
| COAD | Colon adenocarcinoma | E634* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E845E | Silent | 1 |
| COAD | Colon adenocarcinoma | G265V | Missense | 1 |
| COAD | Colon adenocarcinoma | I195V | Missense | 1 |
| COAD | Colon adenocarcinoma | I835F | Missense | 1 |
| COAD | Colon adenocarcinoma | K317N | Missense | 1 |
| COAD | Colon adenocarcinoma | R129Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R253L | Missense | 1 |
| COAD | Colon adenocarcinoma | R253R | Silent | 1 |
| COAD | Colon adenocarcinoma | R328H | Missense | 1 |
| COAD | Colon adenocarcinoma | R525H | Missense | 1 |
| COAD | Colon adenocarcinoma | R753C | Missense | 1 |
| COAD | Colon adenocarcinoma | R905C | Missense | 1 |
| COAD | Colon adenocarcinoma | R928Q | Missense | 1 |
| COAD | Colon adenocarcinoma | W524* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | F394V | Missense | 1 |
| ESCA | Esophageal carcinoma | N246K | Missense | 1 |
| ESCA | Esophageal carcinoma | R829R | Silent | 1 |
| GBM | Glioblastoma multiforme | A41A | Silent | 1 |
| GBM | Glioblastoma multiforme | Q724H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E923D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F273C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L354L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R751* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S891S | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K1039N | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L805P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q65* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | D434H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E528D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R424* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | R457G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K267R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K297* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | M668V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S509N | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1009A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A220A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A89A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D26Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E36K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G418G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G922* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | I611S | Missense | 1 |
| LUAD | Lung adenocarcinoma | K411N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L157V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L194L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L258I | Missense | 1 |
| LUAD | Lung adenocarcinoma | L343L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L936L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P537P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P946S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q910K | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q997* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R1041R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R91* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S503* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S75F | Missense | 1 |
| LUAD | Lung adenocarcinoma | T810I | Missense | 1 |
| LUAD | Lung adenocarcinoma | V61V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | F171L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G213G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | I139M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I653F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q35E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q510H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T149I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F620L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I195I | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R253* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R525H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | W860C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D643N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E1037* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | D980H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E629K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R993P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y943* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | I415M | Missense | 1 |
| READ | Rectum adenocarcinoma | N203S | Missense | 1 |
| READ | Rectum adenocarcinoma | P784R | Missense | 1 |
| READ | Rectum adenocarcinoma | R148H | Missense | 1 |
| READ | Rectum adenocarcinoma | R229Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R753C | Missense | 1 |
| READ | Rectum adenocarcinoma | R921C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | *1055* | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1026K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E172* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E319K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E830E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G578V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P240Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R607* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R618S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R808R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R863* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | I915L | Missense | 1 |
| STAD | Stomach adenocarcinoma | K680* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | L383L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P128S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P563S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R259C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R706C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R753C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R795H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R925G | Missense | 1 |
| STAD | Stomach adenocarcinoma | R925K | Missense | 1 |
| STAD | Stomach adenocarcinoma | R993Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S770S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | L579L | Silent | 1 |
| THCA | Thyroid carcinoma | V178V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A825A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D154Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D26D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D864N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E156E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E277* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E296* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E500* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E547* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G223D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G486G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G959* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K414N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K433N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K59N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L350L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L853V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P175H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1015H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R129Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R885Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R993Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R999I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S370Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S891S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T50M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T956N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V895V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 3.9 | 12 |
| BRCA | Breast invasive carcinoma | 976 | 5.7 | 6.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.9 | 1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 5.7 | 11.8 | 8 |
| ESCA | Esophageal carcinoma | 185 | 2.9 | 2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.9 | 1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.7 | 2 | 4 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2 | 4 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.9 | 4 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.9 | 4 |
| LUAD | Lung adenocarcinoma | 533 | 28.6 | 9.8 | 16 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.9 | 5.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.9 | 2.9 | 4 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1 | 4 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 4 |
| READ | Rectum adenocarcinoma | 122 | 0 | 6.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 8.6 | 4.9 | 12 |
| STAD | Stomach adenocarcinoma | 393 | 5.7 | 9.8 | 4 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.9 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 2.9 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 20 | 19.6 | 20 |