Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | N643S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A406A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D284N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D851N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E254K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E410K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E672K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E727K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L601V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M696V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q192E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V824V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | W642C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A521S | Missense | 1 |
| BRCA | Breast invasive carcinoma | A869A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D518D | Silent | 1 |
| BRCA | Breast invasive carcinoma | D675N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E778Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E836K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P1093A | Missense | 1 |
| BRCA | Breast invasive carcinoma | R724Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | L662F | Missense | 1 |
| COAD | Colon adenocarcinoma | A455V | Missense | 1 |
| COAD | Colon adenocarcinoma | A954T | Missense | 1 |
| COAD | Colon adenocarcinoma | K261Q | Missense | 1 |
| COAD | Colon adenocarcinoma | N148I | Missense | 1 |
| COAD | Colon adenocarcinoma | N643N | Silent | 1 |
| COAD | Colon adenocarcinoma | P680P | Silent | 1 |
| COAD | Colon adenocarcinoma | R499C | Missense | 1 |
| COAD | Colon adenocarcinoma | S1044F | Missense | 1 |
| ESCA | Esophageal carcinoma | K814R | Missense | 1 |
| ESCA | Esophageal carcinoma | R323Q | Missense | 1 |
| GBM | Glioblastoma multiforme | V244V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P237A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R652H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S704F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L632V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G775R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R602P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V558L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E889* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | K61K | Silent | 1 |
| LGG | Brain Lower Grade Glioma | L230V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1093T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R491Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S689N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T653A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q957R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S432G | Missense | 1 |
| LUAD | Lung adenocarcinoma | A69V | Missense | 1 |
| LUAD | Lung adenocarcinoma | D805E | Missense | 1 |
| LUAD | Lung adenocarcinoma | D805Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | F276F | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q684L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q88L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R726L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R890T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S691L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D370Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G402V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W642C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S748P | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | M958V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R953Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V377A | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I920N | Missense | 1 |
| READ | Rectum adenocarcinoma | R499R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D707D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L180S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L437R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L773V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L84F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1092S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P332S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P554S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T417I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V400G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W263* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | D362V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E959E | Silent | 1 |
| STAD | Stomach adenocarcinoma | F109L | Missense | 1 |
| STAD | Stomach adenocarcinoma | K392N | Missense | 1 |
| STAD | Stomach adenocarcinoma | M1029I | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1084P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R147H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R491Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R499H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R602H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R939C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R939R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R953* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | T335A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T415A | Missense | 1 |
| STAD | Stomach adenocarcinoma | W623* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D284E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D394Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E672D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E840* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I920S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P399P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q961Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R190Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R491Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R512Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R572* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S894S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T844A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W457C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.8 | 11.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 11.8 | 7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.8 | 9.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 5.9 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 3.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.9 | 5.8 | 16.7 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.9 | 9.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 5.9 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 5.9 | 10.5 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 17.6 | 12.8 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 17.6 | 10.5 | 33.3 |