Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E439K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I417T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K126K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R493* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V278V | Silent | 1 |
| BRCA | Breast invasive carcinoma | I176V | Missense | 1 |
| BRCA | Breast invasive carcinoma | I372I | Silent | 1 |
| CESC | Cervical and endocervical cancers | I372I | Silent | 1 |
| COAD | Colon adenocarcinoma | F233L | Missense | 1 |
| COAD | Colon adenocarcinoma | H332H | Silent | 1 |
| COAD | Colon adenocarcinoma | L343P | Missense | 1 |
| COAD | Colon adenocarcinoma | P275P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q344Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R493* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | D268Y | Missense | 1 |
| ESCA | Esophageal carcinoma | D421H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P381P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q271* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T189S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I424I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N514D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A193A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E266D | Missense | 1 |
| LUAD | Lung adenocarcinoma | F440F | Silent | 1 |
| LUAD | Lung adenocarcinoma | F495L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L442L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R214Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R478* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | V280E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E243K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A490T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T267T | Silent | 1 |
| READ | Rectum adenocarcinoma | L150I | Missense | 1 |
| READ | Rectum adenocarcinoma | R183Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | *516* | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L301L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R180W | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R503L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E505* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F233L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K126N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L364S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R183L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R303* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S239F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 13.3 | 8.3 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 6.7 | 4.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 6.7 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 20 | 8.3 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 0 | 8.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 0 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 4.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 20 | 16.7 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 8.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 13.3 | 0 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 4.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 4.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 20.8 | 33.3 |