Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A158A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E490K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L264L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V438V | Silent | 1 |
| BRCA | Breast invasive carcinoma | L526L | Silent | 1 |
| BRCA | Breast invasive carcinoma | W230C | Missense | 1 |
| CESC | Cervical and endocervical cancers | E521* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | K139N | Missense | 1 |
| COAD | Colon adenocarcinoma | A434T | Missense | 1 |
| COAD | Colon adenocarcinoma | P105H | Missense | 1 |
| COAD | Colon adenocarcinoma | R473C | Missense | 1 |
| COAD | Colon adenocarcinoma | R494* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | D409N | Missense | 1 |
| ESCA | Esophageal carcinoma | R276Q | Missense | 1 |
| ESCA | Esophageal carcinoma | Y352H | Missense | 1 |
| GBM | Glioblastoma multiforme | R233* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F423S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L458L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G322E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L300F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G292G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | I339V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R104Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R150Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R177Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | D414N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E351D | Missense | 1 |
| LUAD | Lung adenocarcinoma | N342H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P78S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q157* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R118H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D463N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S446F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R133W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R357H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A425V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F115F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P114S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P489L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R477G | Missense | 1 |
| STAD | Stomach adenocarcinoma | A223T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C298R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G220E | Missense | 1 |
| STAD | Stomach adenocarcinoma | R195W | Missense | 1 |
| STAD | Stomach adenocarcinoma | V144A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A124A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G285S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R104Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R195W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R367* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R369H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 37.5 | 2.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 2.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.6 | 20 |
| COAD | Colon adenocarcinoma | 367 | 0 | 7.9 | 20 |
| ESCA | Esophageal carcinoma | 185 | 0 | 7.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 20 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 2.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 12.5 | 10.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 13.2 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 5.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 10.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 13.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 10.5 | 20 |