Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| CESC | Cervical and endocervical cancers | Q38E | Missense | 2 |
| COAD | Colon adenocarcinoma | T794T | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E315Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q522* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q652Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R466L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R562K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R899* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S189* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | W658R | Missense | 1 |
| BRCA | Breast invasive carcinoma | D717Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | R40C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S887S | Silent | 1 |
| CESC | Cervical and endocervical cancers | E751E | Silent | 1 |
| CESC | Cervical and endocervical cancers | H279Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | K388N | Missense | 1 |
| CESC | Cervical and endocervical cancers | P81A | Missense | 1 |
| CESC | Cervical and endocervical cancers | Y766Y | Silent | 1 |
| COAD | Colon adenocarcinoma | A646V | Missense | 1 |
| COAD | Colon adenocarcinoma | D215D | Silent | 1 |
| COAD | Colon adenocarcinoma | E286* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | K249N | Missense | 1 |
| COAD | Colon adenocarcinoma | K88N | Missense | 1 |
| COAD | Colon adenocarcinoma | R233W | Missense | 1 |
| COAD | Colon adenocarcinoma | R391C | Missense | 1 |
| COAD | Colon adenocarcinoma | R391H | Missense | 1 |
| COAD | Colon adenocarcinoma | R526H | Missense | 1 |
| COAD | Colon adenocarcinoma | R731H | Missense | 1 |
| COAD | Colon adenocarcinoma | R894H | Missense | 1 |
| COAD | Colon adenocarcinoma | T418T | Silent | 1 |
| COAD | Colon adenocarcinoma | T794A | Missense | 1 |
| COAD | Colon adenocarcinoma | V698M | Missense | 1 |
| COAD | Colon adenocarcinoma | Y766Y | Silent | 1 |
| ESCA | Esophageal carcinoma | A813T | Missense | 1 |
| ESCA | Esophageal carcinoma | G605G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F553F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H625R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | H171H | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y746C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A556T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K71N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R565Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V221F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G859E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R322S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A482T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E125* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E166D | Missense | 1 |
| LUAD | Lung adenocarcinoma | F800L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G167W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G852W | Missense | 1 |
| LUAD | Lung adenocarcinoma | I198M | Missense | 1 |
| LUAD | Lung adenocarcinoma | I198V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M111I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q258* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R232L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V830L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V830V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A529S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E478Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E498E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G120G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | I801I | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | D468E | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L323L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | T794T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L780I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R910H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S619S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G275C | Missense | 1 |
| READ | Rectum adenocarcinoma | G490G | Silent | 1 |
| SARC | Sarcoma | P332H | Missense | 1 |
| SARC | Sarcoma | Y697S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C440F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L274V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L288L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P241L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P424S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P519S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q192* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R55R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S254L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S619S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S727F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T841T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A835A | Silent | 1 |
| STAD | Stomach adenocarcinoma | E689K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E877K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G609S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G849G | Silent | 1 |
| STAD | Stomach adenocarcinoma | L390L | Silent | 1 |
| STAD | Stomach adenocarcinoma | N382S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P392S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R135R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R374* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R391C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R40L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R894C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S372S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V219A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V761V | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | E647* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | L570F | Missense | 1 |
| THYM | Thymoma | A799T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A308T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A5T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A797A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E559* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R174R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R327S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R47Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R47W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R747H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S887S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T824I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V221V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y465C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y661C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.9 | 5.3 | 30 |
| BRCA | Breast invasive carcinoma | 976 | 2.9 | 2.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.9 | 6.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 14.7 | 14.5 | 10 |
| ESCA | Esophageal carcinoma | 185 | 2.9 | 1.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.9 | 1.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.9 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 2.9 | 13.2 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 8.8 | 2.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 5.9 | 1.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.9 | 2.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.9 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.8 | 9.2 | 10 |
| STAD | Stomach adenocarcinoma | 393 | 17.6 | 11.8 | 10 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.3 | 10 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 1.3 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 11.8 | 10 |