Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | D150N | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | Q82* | Nonsense | 2 |
| SKCM | Skin Cutaneous Melanoma | R669R | Silent | 2 |
| STAD | Stomach adenocarcinoma | G479D | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K535N | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E237* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E293Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E310K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E35Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E724* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | F559V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F712F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | H717Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K496N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K603N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M10I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q519L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R401C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R86T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S709* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T360T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | T707P | Missense | 1 |
| BRCA | Breast invasive carcinoma | E101* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G8R | Missense | 1 |
| BRCA | Breast invasive carcinoma | K604N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R576I | Missense | 1 |
| BRCA | Breast invasive carcinoma | R824H | Missense | 1 |
| CESC | Cervical and endocervical cancers | S429L | Missense | 1 |
| COAD | Colon adenocarcinoma | A487E | Missense | 1 |
| COAD | Colon adenocarcinoma | A565A | Silent | 1 |
| COAD | Colon adenocarcinoma | D527D | Silent | 1 |
| COAD | Colon adenocarcinoma | D706N | Missense | 1 |
| COAD | Colon adenocarcinoma | E312* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E419D | Missense | 1 |
| COAD | Colon adenocarcinoma | E52D | Missense | 1 |
| COAD | Colon adenocarcinoma | G388G | Silent | 1 |
| COAD | Colon adenocarcinoma | H421R | Missense | 1 |
| COAD | Colon adenocarcinoma | I782S | Missense | 1 |
| COAD | Colon adenocarcinoma | T472M | Missense | 1 |
| COAD | Colon adenocarcinoma | V531V | Silent | 1 |
| GBM | Glioblastoma multiforme | N149N | Silent | 1 |
| GBM | Glioblastoma multiforme | S215C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E267K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L675L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N252N | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P663S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R70H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T582N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A537V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E103K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G8E | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A859V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A537V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E534K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S185L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G8G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P203L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S215C | Missense | 1 |
| LUAD | Lung adenocarcinoma | C708Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | C716R | Missense | 1 |
| LUAD | Lung adenocarcinoma | D125D | Silent | 1 |
| LUAD | Lung adenocarcinoma | D543H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E323K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E463D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E847Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F623F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G161C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G398* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G5C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G8G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G8W | Missense | 1 |
| LUAD | Lung adenocarcinoma | I118N | Missense | 1 |
| LUAD | Lung adenocarcinoma | I486I | Silent | 1 |
| LUAD | Lung adenocarcinoma | N540N | Silent | 1 |
| LUAD | Lung adenocarcinoma | N864K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P720P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q3H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q4H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q607R | Missense | 1 |
| LUAD | Lung adenocarcinoma | R497R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S344Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C38F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P663S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S405F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T626T | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | C478S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I230V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P739P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | C705C | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P720S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R401C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E286D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P591P | Silent | 1 |
| READ | Rectum adenocarcinoma | C705C | Silent | 1 |
| READ | Rectum adenocarcinoma | E24D | Missense | 1 |
| READ | Rectum adenocarcinoma | E272E | Silent | 1 |
| READ | Rectum adenocarcinoma | F61F | Silent | 1 |
| READ | Rectum adenocarcinoma | T299T | Silent | 1 |
| SARC | Sarcoma | K551K | Silent | 1 |
| SARC | Sarcoma | P124S | Missense | 1 |
| SARC | Sarcoma | S196P | Missense | 1 |
| SARC | Sarcoma | Y261H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A537A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A565T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D174N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D245N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D301N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D543N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D715N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D838N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E128K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E171K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E267K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E271K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E371K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E534K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E627K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F115L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F85L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G207* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | G219G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G294E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G311E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G398R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G493E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G599R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G632E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G865E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I25I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K204K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K586K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K603K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L151* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | L202L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L675L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P90S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q567Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R117R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R281K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R636K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R68Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S346S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S447L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V177V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V89V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W622L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A210T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A791V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D397D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E749D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F559L | Missense | 1 |
| STAD | Stomach adenocarcinoma | K285M | Missense | 1 |
| STAD | Stomach adenocarcinoma | K613T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K796N | Missense | 1 |
| STAD | Stomach adenocarcinoma | N538N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P465P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q199H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q229* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R295T | Missense | 1 |
| STAD | Stomach adenocarcinoma | T105I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G699* | Nonsense | 1 |
| THCA | Thyroid carcinoma | A487T | Missense | 1 |
| THCA | Thyroid carcinoma | T304T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A257V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C137* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C696C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C792C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E775D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F192L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I610I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I826I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K577N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K736N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L846M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R156I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R645C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R665I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R667C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S262N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S357S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T360T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y261C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.9 | 9.8 | 23.1 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 3.3 | 7.7 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.8 | 5.7 | 7.7 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2 | 0.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.9 | 3.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2 | 1.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.7 | 12.2 | 7.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 2 | 2.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2 | 1.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2 | 0.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.8 | 0.8 | 0 |
| SARC | Sarcoma | 247 | 2 | 2.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 29.4 | 25.2 | 30.8 |
| STAD | Stomach adenocarcinoma | 393 | 5.9 | 9.8 | 7.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 7.7 |
| THCA | Thyroid carcinoma | 495 | 2 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 11.4 | 7.7 |