Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | L301L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R108R | Silent | 1 |
| BRCA | Breast invasive carcinoma | R103Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R408R | Silent | 1 |
| BRCA | Breast invasive carcinoma | V45F | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q133K | Missense | 1 |
| COAD | Colon adenocarcinoma | A348T | Missense | 1 |
| COAD | Colon adenocarcinoma | L19L | Silent | 1 |
| COAD | Colon adenocarcinoma | R212W | Missense | 1 |
| COAD | Colon adenocarcinoma | R259H | Missense | 1 |
| COAD | Colon adenocarcinoma | T279T | Silent | 1 |
| COAD | Colon adenocarcinoma | V332V | Silent | 1 |
| COAD | Colon adenocarcinoma | Y303Y | Silent | 1 |
| ESCA | Esophageal carcinoma | D306D | Silent | 1 |
| GBM | Glioblastoma multiforme | G358G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E182K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K91K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R292H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R395Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y303* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V45V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N164S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C49C | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E262D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K239N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A127A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | C82C | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K87* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | L118L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L217M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R286W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Y205C | Missense | 1 |
| SARC | Sarcoma | R249C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R129C | Missense | 1 |
| STAD | Stomach adenocarcinoma | D291Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | F269F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G216R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L135L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R144H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R265H | Missense | 1 |
| STAD | Stomach adenocarcinoma | V258D | Missense | 1 |
| STAD | Stomach adenocarcinoma | V258I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A283S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C23C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E150K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G294G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K53N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K91K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q288H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q57H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R395W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V236M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 10 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5 | 6.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 20 | 10 | 0 |
| ESCA | Esophageal carcinoma | 185 | 5 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 5 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5 | 10 | 50 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5 | 6.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 10 | 0 | 50 |
| LUAD | Lung adenocarcinoma | 533 | 5 | 3.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 6.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 3.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 10 | 20 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 3.3 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 15 | 20 | 0 |