Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | P670P | Silent | 3 |
| LIHC | Liver hepatocellular carcinoma | T35S | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R220Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D687Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F178L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G313E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G737R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I869T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K446M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L561F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L858F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R15S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R16T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R335T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R515G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R699* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S30L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S397Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S51S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S552C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S774C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S831C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y166C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A641V | Missense | 1 |
| BRCA | Breast invasive carcinoma | D828N | Missense | 1 |
| BRCA | Breast invasive carcinoma | N712K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P558Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R721C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S193C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S255F | Missense | 1 |
| CESC | Cervical and endocervical cancers | L454F | Missense | 1 |
| COAD | Colon adenocarcinoma | A74T | Missense | 1 |
| COAD | Colon adenocarcinoma | C305Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D574G | Missense | 1 |
| COAD | Colon adenocarcinoma | E302* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E320K | Missense | 1 |
| COAD | Colon adenocarcinoma | G266G | Silent | 1 |
| COAD | Colon adenocarcinoma | G617E | Missense | 1 |
| COAD | Colon adenocarcinoma | I303M | Missense | 1 |
| COAD | Colon adenocarcinoma | K348N | Missense | 1 |
| COAD | Colon adenocarcinoma | K761K | Silent | 1 |
| COAD | Colon adenocarcinoma | N487K | Missense | 1 |
| COAD | Colon adenocarcinoma | N753N | Silent | 1 |
| COAD | Colon adenocarcinoma | P670L | Missense | 1 |
| COAD | Colon adenocarcinoma | P670T | Missense | 1 |
| COAD | Colon adenocarcinoma | S304Y | Missense | 1 |
| COAD | Colon adenocarcinoma | T569T | Silent | 1 |
| COAD | Colon adenocarcinoma | W264* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | I432V | Missense | 1 |
| ESCA | Esophageal carcinoma | K41N | Missense | 1 |
| ESCA | Esophageal carcinoma | L226* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | M253L | Missense | 1 |
| ESCA | Esophageal carcinoma | S367N | Missense | 1 |
| ESCA | Esophageal carcinoma | V252V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E151Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E785K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G246G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G524V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L461L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L858F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N755N | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R202T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V11M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I861M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P489S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T430T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D249N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D847D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | K211R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G19G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | H457H | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L858V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M100R | Missense | 1 |
| LUAD | Lung adenocarcinoma | D553N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E142Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G194A | Missense | 1 |
| LUAD | Lung adenocarcinoma | H796Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | I779I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L806V | Missense | 1 |
| LUAD | Lung adenocarcinoma | N240S | Missense | 1 |
| LUAD | Lung adenocarcinoma | N753N | Silent | 1 |
| LUAD | Lung adenocarcinoma | P583A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P583T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S204S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S283L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S426L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S427C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S552C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S676L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S86T | Missense | 1 |
| LUAD | Lung adenocarcinoma | V663L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V678L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D640H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E61Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P851S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q374E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S873* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | T569K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K761N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P670T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D784Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R187L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R220* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | V673I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E325* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | L198V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P672P | Silent | 1 |
| READ | Rectum adenocarcinoma | A669V | Missense | 1 |
| READ | Rectum adenocarcinoma | D249N | Missense | 1 |
| READ | Rectum adenocarcinoma | R16I | Missense | 1 |
| READ | Rectum adenocarcinoma | R65H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E530G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K145K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L809L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N739I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P438L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P521T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P573R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P851S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R133R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R220Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S114L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A502A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C279W | Missense | 1 |
| STAD | Stomach adenocarcinoma | G132* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | G524G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G608C | Missense | 1 |
| STAD | Stomach adenocarcinoma | H112N | Missense | 1 |
| STAD | Stomach adenocarcinoma | H457N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K481R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L585L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L883R | Missense | 1 |
| STAD | Stomach adenocarcinoma | N520I | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q386R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R220L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S51L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S566N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T215A | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y307D | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y821H | Missense | 1 |
| THCA | Thyroid carcinoma | Y818H | Missense | 1 |
| THYM | Thymoma | A641A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A269V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E238E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F127L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K258E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K8N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L226V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L470L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N753N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q134H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R511I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R539W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R615Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R65C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R65H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R783* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S58L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.3 | 14.6 | 11.1 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 23.3 | 8.9 | 22.2 |
| ESCA | Esophageal carcinoma | 185 | 3.3 | 3.3 | 11.1 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10 | 4.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.3 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.3 | 1.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.7 | 3.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 10 | 13 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.1 | 11.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.4 | 11.1 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.3 | 0.8 | 11.1 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 10 | 6.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 10 | 11.4 | 11.1 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.8 | 0 |
| THYM | Thymoma | 119 | 3.3 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10 | 11.4 | 11.1 |