Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | T160T | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E601Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F346F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K521E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L377F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L469L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M265I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q221* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R103R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S583I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S604C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S693F | Missense | 1 |
| BRCA | Breast invasive carcinoma | D303H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E383K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G691G | Silent | 1 |
| BRCA | Breast invasive carcinoma | L529V | Missense | 1 |
| BRCA | Breast invasive carcinoma | M144I | Missense | 1 |
| BRCA | Breast invasive carcinoma | M319L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q95H | Missense | 1 |
| CESC | Cervical and endocervical cancers | L219L | Silent | 1 |
| COAD | Colon adenocarcinoma | H471R | Missense | 1 |
| COAD | Colon adenocarcinoma | K143E | Missense | 1 |
| COAD | Colon adenocarcinoma | K650N | Missense | 1 |
| COAD | Colon adenocarcinoma | R101* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R103Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R286* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R458H | Missense | 1 |
| GBM | Glioblastoma multiforme | E421K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K468N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V206V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | K223* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L338H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N477T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E388* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | G163D | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R103Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R286* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | I491V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q387R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A332V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E364* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | K459E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R458H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V581E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R101* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R286* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R307H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D290N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L722L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P207S | Missense | 1 |
| STAD | Stomach adenocarcinoma | A332T | Missense | 1 |
| STAD | Stomach adenocarcinoma | R286Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R575C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C325Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D665Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D725Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E142D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F346F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I671M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N216H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q441H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R101Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R439M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R682C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T354T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V182V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 25 | 15.2 | 11.1 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 13 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 8.3 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 8.7 | 22.2 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.3 | 2.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 4.3 | 11.1 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 11.1 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 4.3 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 11.1 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 0 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 6.5 | 11.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 22.2 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 8.3 | 4.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 6.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 41.7 | 21.7 | 0 |