Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | R59* | Nonsense | 2 |
| THCA | Thyroid carcinoma | S240S | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | *1961* | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D1141Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1448Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E697* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | H431D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1649I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P560L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1082K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q271E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q565Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q726* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q850* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1131T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R5W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1181F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1246C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1698S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S240S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S476Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S527L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T614S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V1661V | Silent | 1 |
| BRCA | Breast invasive carcinoma | A688G | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1410G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G1834G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G621G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G642G | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q1956K | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1438C | Missense | 1 |
| BRCA | Breast invasive carcinoma | R706C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1310C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1369F | Missense | 1 |
| BRCA | Breast invasive carcinoma | S144C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S609C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S701F | Missense | 1 |
| BRCA | Breast invasive carcinoma | V606G | Missense | 1 |
| BRCA | Breast invasive carcinoma | V877V | Silent | 1 |
| CESC | Cervical and endocervical cancers | D496H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1512K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1837K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E273K | Missense | 1 |
| CESC | Cervical and endocervical cancers | H1304Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1016F | Missense | 1 |
| CESC | Cervical and endocervical cancers | L705V | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1800W | Missense | 1 |
| CESC | Cervical and endocervical cancers | S270C | Missense | 1 |
| COAD | Colon adenocarcinoma | A1895T | Missense | 1 |
| COAD | Colon adenocarcinoma | A1948A | Silent | 1 |
| COAD | Colon adenocarcinoma | A202V | Missense | 1 |
| COAD | Colon adenocarcinoma | A35T | Missense | 1 |
| COAD | Colon adenocarcinoma | A67T | Missense | 1 |
| COAD | Colon adenocarcinoma | A799A | Silent | 1 |
| COAD | Colon adenocarcinoma | C1912Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D594N | Missense | 1 |
| COAD | Colon adenocarcinoma | E1186* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G522G | Silent | 1 |
| COAD | Colon adenocarcinoma | I1341V | Missense | 1 |
| COAD | Colon adenocarcinoma | K1946R | Missense | 1 |
| COAD | Colon adenocarcinoma | K733E | Missense | 1 |
| COAD | Colon adenocarcinoma | K922I | Missense | 1 |
| COAD | Colon adenocarcinoma | P1214P | Silent | 1 |
| COAD | Colon adenocarcinoma | P1543L | Missense | 1 |
| COAD | Colon adenocarcinoma | P428P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1596Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R695K | Missense | 1 |
| COAD | Colon adenocarcinoma | S237S | Silent | 1 |
| COAD | Colon adenocarcinoma | S256S | Silent | 1 |
| COAD | Colon adenocarcinoma | S592L | Missense | 1 |
| COAD | Colon adenocarcinoma | T1520P | Missense | 1 |
| ESCA | Esophageal carcinoma | D1244V | Missense | 1 |
| ESCA | Esophageal carcinoma | D1324N | Missense | 1 |
| ESCA | Esophageal carcinoma | R1022W | Missense | 1 |
| ESCA | Esophageal carcinoma | S1023R | Missense | 1 |
| ESCA | Esophageal carcinoma | T1520T | Silent | 1 |
| GBM | Glioblastoma multiforme | V599F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I1881V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1197A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1232L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1826S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q794E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1791C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1685L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1760S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S387F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T1381T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | C1705C | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | D1384N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | D765Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1856L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1116K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1827Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V470V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D1099Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L860F | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M424L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q293Q | Silent | 1 |
| LGG | Brain Lower Grade Glioma | Q758H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R535W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A1399D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A1652P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E1096* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | P1075A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P428R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P911R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q116* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q320Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S1167G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1414S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S1522T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V1108L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1878A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1895A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A516P | Missense | 1 |
| LUAD | Lung adenocarcinoma | A576G | Missense | 1 |
| LUAD | Lung adenocarcinoma | A970S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1095A | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1159K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1574Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1877V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1835V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1870G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G42G | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1223V | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1911R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1935P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1581S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1928M | Missense | 1 |
| LUAD | Lung adenocarcinoma | S238C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S242S | Silent | 1 |
| LUAD | Lung adenocarcinoma | V915E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G1205E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G1894G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | H1245N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H761N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1022Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R706H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V1868F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A1060A | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | G522G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | L187F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1214S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T1831S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D520Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E1851G | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G1291G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | H22H | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | I1842I | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L453L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R535W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S663N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D1794N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | F139F | Silent | 1 |
| PRAD | Prostate adenocarcinoma | N944I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P1737S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q565K | Missense | 1 |
| READ | Rectum adenocarcinoma | E554D | Missense | 1 |
| READ | Rectum adenocarcinoma | G1722G | Silent | 1 |
| READ | Rectum adenocarcinoma | K304N | Missense | 1 |
| READ | Rectum adenocarcinoma | P1523P | Silent | 1 |
| SARC | Sarcoma | P1265L | Missense | 1 |
| SARC | Sarcoma | P350S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1528F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G503G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I1842I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1643I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L975I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1035L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1203L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1250P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1312L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1312S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1392S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1429L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1843S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P467S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P750Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P815S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1592* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R962C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1361S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1570F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S3F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S648S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S712S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S974F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y1632Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | A633T | Missense | 1 |
| STAD | Stomach adenocarcinoma | I1566M | Missense | 1 |
| STAD | Stomach adenocarcinoma | L519L | Silent | 1 |
| STAD | Stomach adenocarcinoma | N500H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P318P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P980P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q1876H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q310K | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q311H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q313Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q7* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1022W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R637R | Silent | 1 |
| STAD | Stomach adenocarcinoma | T485T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V403V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V470A | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y272N | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G1028G | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S966R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T1449K | Missense | 1 |
| THYM | Thymoma | E1057D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1077T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1626T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1948T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A281T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D932Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1243D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1923D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1142G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1457R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G232D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1702Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1173T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1318N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1748T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K512E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L466I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P350P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P980P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q122H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1553H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q313Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q343L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1068Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1791H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1907Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1959Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R616Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R706H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R719Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S769Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S871C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1067I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V328A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V721V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.2 | 7.6 | 30 |
| BRCA | Breast invasive carcinoma | 976 | 7.7 | 5.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 5.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.8 | 8.8 | 10 |
| ESCA | Esophageal carcinoma | 185 | 1.5 | 2.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.1 | 4.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.1 | 2.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.5 | 2.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.1 | 4.7 | 20 |
| LUAD | Lung adenocarcinoma | 533 | 9.2 | 8.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 1.5 | 3.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.1 | 1.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 6.2 | 2.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.5 | 2.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.1 | 1.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.3 | 9.4 | 10 |
| STAD | Stomach adenocarcinoma | 393 | 10.8 | 5.3 | 30 |
| TGCT | Testicular Germ Cell Tumors | 147 | 1.5 | 1.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 3.1 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0.6 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 17.1 | 0 |