Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | S322L | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | G194G | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | T84T | Silent | 1 |
| BRCA | Breast invasive carcinoma | E217K | Missense | 1 |
| BRCA | Breast invasive carcinoma | H262H | Silent | 1 |
| BRCA | Breast invasive carcinoma | L188L | Silent | 1 |
| BRCA | Breast invasive carcinoma | T229T | Silent | 1 |
| BRCA | Breast invasive carcinoma | V102M | Missense | 1 |
| CESC | Cervical and endocervical cancers | E235K | Missense | 1 |
| CESC | Cervical and endocervical cancers | H262H | Silent | 1 |
| CESC | Cervical and endocervical cancers | V204V | Silent | 1 |
| COAD | Colon adenocarcinoma | A143T | Missense | 1 |
| COAD | Colon adenocarcinoma | E154D | Missense | 1 |
| COAD | Colon adenocarcinoma | G248E | Missense | 1 |
| COAD | Colon adenocarcinoma | H190R | Missense | 1 |
| COAD | Colon adenocarcinoma | K145K | Silent | 1 |
| COAD | Colon adenocarcinoma | R247R | Silent | 1 |
| COAD | Colon adenocarcinoma | S191S | Silent | 1 |
| ESCA | Esophageal carcinoma | A288A | Silent | 1 |
| ESCA | Esophageal carcinoma | L270L | Silent | 1 |
| ESCA | Esophageal carcinoma | P164L | Missense | 1 |
| ESCA | Esophageal carcinoma | Q66* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | L14L | Silent | 1 |
| GBM | Glioblastoma multiforme | R247R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A143T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F57F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F57L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T201M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | W276C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V83V | Silent | 1 |
| LAML | Acute Myeloid Leukemia | R193H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P122L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V192I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E166G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E241E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G332G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L309Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F29L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G169V | Missense | 1 |
| LUAD | Lung adenocarcinoma | K47* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | T289T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E126D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N58S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H190Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P59H | Missense | 1 |
| READ | Rectum adenocarcinoma | A288T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A196P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D271N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D56N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E152E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E195K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E49K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G285R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K55K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P205S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P238P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P42S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T207T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V192V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A128T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A288V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D302N | Missense | 1 |
| STAD | Stomach adenocarcinoma | G78S | Missense | 1 |
| STAD | Stomach adenocarcinoma | L14L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P122L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R177R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R193L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R296H | Missense | 1 |
| STAD | Stomach adenocarcinoma | T201A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T84T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V173V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A121V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D283Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E126D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G197G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P8S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R296C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.3 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 10 | 4.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 6.7 | 2.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10 | 12.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.7 | 2.1 | 50 |
| GBM | Glioblastoma multiforme | 283 | 6.7 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.3 | 6.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.3 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 2.1 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.7 | 4.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.3 | 4.3 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.3 | 17 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.3 | 17 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.3 | 10.6 | 0 |