Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R322Q | Missense | 3 |
| COAD | Colon adenocarcinoma | R486Q | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D313Y | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | L57V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M217V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P393L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R338T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S303L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S75* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V56F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y435* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | I525K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P646P | Silent | 1 |
| BRCA | Breast invasive carcinoma | P89P | Silent | 1 |
| CESC | Cervical and endocervical cancers | E497K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E66K | Missense | 1 |
| COAD | Colon adenocarcinoma | D195D | Silent | 1 |
| COAD | Colon adenocarcinoma | E17* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E425* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G357D | Missense | 1 |
| COAD | Colon adenocarcinoma | I449L | Missense | 1 |
| COAD | Colon adenocarcinoma | K539K | Silent | 1 |
| COAD | Colon adenocarcinoma | M410T | Missense | 1 |
| COAD | Colon adenocarcinoma | M585I | Missense | 1 |
| COAD | Colon adenocarcinoma | P380P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q292Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q632Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R158T | Missense | 1 |
| COAD | Colon adenocarcinoma | R486* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R506* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R574Q | Missense | 1 |
| COAD | Colon adenocarcinoma | T203P | Missense | 1 |
| ESCA | Esophageal carcinoma | G468G | Silent | 1 |
| ESCA | Esophageal carcinoma | I605V | Missense | 1 |
| ESCA | Esophageal carcinoma | N315H | Missense | 1 |
| ESCA | Esophageal carcinoma | V498I | Missense | 1 |
| ESCA | Esophageal carcinoma | W556L | Missense | 1 |
| GBM | Glioblastoma multiforme | K473R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L230V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N570S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P418L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R112K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R255K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S179A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E545E | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A518T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G9S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I471V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P120S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T203M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V194V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E257K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R456S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S396S | Silent | 1 |
| LUAD | Lung adenocarcinoma | D128Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | D195N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E204K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G151V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G299* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H101R | Missense | 1 |
| LUAD | Lung adenocarcinoma | N462S | Missense | 1 |
| LUAD | Lung adenocarcinoma | N488Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | P429S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P89P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R191G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R255I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E204* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | E257Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R326G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S37L | Missense | 1 |
| READ | Rectum adenocarcinoma | A136T | Missense | 1 |
| READ | Rectum adenocarcinoma | D620N | Missense | 1 |
| READ | Rectum adenocarcinoma | L230H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F490F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G415E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P393L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P393S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R251W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R335C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S367F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y435H | Missense | 1 |
| STAD | Stomach adenocarcinoma | C13Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | G617D | Missense | 1 |
| STAD | Stomach adenocarcinoma | K280I | Missense | 1 |
| STAD | Stomach adenocarcinoma | L26P | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q438E | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q482* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R322Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R486* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S364F | Missense | 1 |
| STAD | Stomach adenocarcinoma | S535C | Missense | 1 |
| STAD | Stomach adenocarcinoma | V369V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V477A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A269T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A465T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E615K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G595R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K404* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K470Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N44H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P380P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R169Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R335H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R506Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S364S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S365S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T54I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W556L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 7.1 | 18.2 |
| BRCA | Breast invasive carcinoma | 976 | 11.8 | 1.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 29.4 | 10.7 | 36.4 |
| ESCA | Esophageal carcinoma | 185 | 5.9 | 4.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 7.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.9 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.9 | 3.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.9 | 2.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.9 | 11.9 | 9.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.4 | 9.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 5.9 | 8.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.9 | 10.7 | 18.2 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 17.6 | 19 | 9.1 |