Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | G293E | Missense | 3 |
| COAD | Colon adenocarcinoma | F576L | Missense | 2 |
| LIHC | Liver hepatocellular carcinoma | Q377L | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | D738N | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | E206K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | E626K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | F647F | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | L730L | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | R518* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | *982* | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E600Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E865Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K370K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R718C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R925H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S317C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | W792R | Missense | 1 |
| BRCA | Breast invasive carcinoma | A287V | Missense | 1 |
| BRCA | Breast invasive carcinoma | D790N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E813Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | F338L | Missense | 1 |
| BRCA | Breast invasive carcinoma | I480I | Silent | 1 |
| BRCA | Breast invasive carcinoma | L920L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P416L | Missense | 1 |
| BRCA | Breast invasive carcinoma | S284L | Missense | 1 |
| CESC | Cervical and endocervical cancers | D184N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E939Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | I295M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L76L | Silent | 1 |
| COAD | Colon adenocarcinoma | A368V | Missense | 1 |
| COAD | Colon adenocarcinoma | A888S | Missense | 1 |
| COAD | Colon adenocarcinoma | D350V | Missense | 1 |
| COAD | Colon adenocarcinoma | D737N | Missense | 1 |
| COAD | Colon adenocarcinoma | E643K | Missense | 1 |
| COAD | Colon adenocarcinoma | L745L | Silent | 1 |
| COAD | Colon adenocarcinoma | P728T | Missense | 1 |
| COAD | Colon adenocarcinoma | R51Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R65C | Missense | 1 |
| COAD | Colon adenocarcinoma | R925C | Missense | 1 |
| COAD | Colon adenocarcinoma | R925R | Silent | 1 |
| COAD | Colon adenocarcinoma | S151Y | Missense | 1 |
| COAD | Colon adenocarcinoma | S605L | Missense | 1 |
| COAD | Colon adenocarcinoma | S773* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T604A | Missense | 1 |
| ESCA | Esophageal carcinoma | D737A | Missense | 1 |
| ESCA | Esophageal carcinoma | L934L | Silent | 1 |
| ESCA | Esophageal carcinoma | P896S | Missense | 1 |
| ESCA | Esophageal carcinoma | R925H | Missense | 1 |
| ESCA | Esophageal carcinoma | S774A | Missense | 1 |
| GBM | Glioblastoma multiforme | E643K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A588S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D638H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E32D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E383* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K300K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L45L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L801F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R95R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S928C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T639A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V596V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | E5D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | H42N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V659L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H530P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A181V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R160I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A917A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E3E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K260* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | L364L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | M751T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M778T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P746P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P812P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R489R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R597R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R6G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R718H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S267* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | V57A | Missense | 1 |
| LUAD | Lung adenocarcinoma | A758S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A955V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A959S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D923E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E777Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G114* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G49W | Missense | 1 |
| LUAD | Lung adenocarcinoma | K106N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L11L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L636* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | L730L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M104I | Missense | 1 |
| LUAD | Lung adenocarcinoma | N642K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P249S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P291T | Missense | 1 |
| LUAD | Lung adenocarcinoma | P391Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | P391T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q944H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R108I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R508R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R826G | Missense | 1 |
| LUAD | Lung adenocarcinoma | S296I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S496* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S712P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S765S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S897F | Missense | 1 |
| LUAD | Lung adenocarcinoma | T437K | Missense | 1 |
| LUAD | Lung adenocarcinoma | V929V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A213P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A758T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D930Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E552Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E555D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I7T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L499L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L936* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | P974H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q828* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R489R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R535N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R65S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V341L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V64F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D629N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F576F | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R925H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G474W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q219Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S899Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N834N | Silent | 1 |
| READ | Rectum adenocarcinoma | A676V | Missense | 1 |
| READ | Rectum adenocarcinoma | R962Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C615Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C729C | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D24N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D494N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D539N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D737N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D794N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E256D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E30K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E343K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E34K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E643K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E82K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F282F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F327F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F848F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G107E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G564E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G754R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G804R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I480I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I631I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I906I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K419N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K769K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L464L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L48F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L801F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M503I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P147S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P249P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P372L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P409S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P674S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P883P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q377* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R101Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R163Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R16K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R192K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R518Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S395L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S471F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S471S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S765N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S892F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S966F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T294A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V39I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W740* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | C615C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E265E | Silent | 1 |
| STAD | Stomach adenocarcinoma | G359G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G474R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G616S | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q288R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R916C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T805T | Silent | 1 |
| THCA | Thyroid carcinoma | N642N | Silent | 1 |
| THCA | Thyroid carcinoma | V534I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E32D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E500K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E82E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F486L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G736G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L531L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N180S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P710P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q4H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q818* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R826M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R962W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S317Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S605L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S665Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S915S | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.6 | 4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.6 | 4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 1.8 | 2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 3.6 | 9.3 | 7.1 |
| ESCA | Esophageal carcinoma | 185 | 1.8 | 2.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.3 | 4 | 7.1 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 12.7 | 4.7 | 14.3 |
| LUAD | Lung adenocarcinoma | 533 | 9.1 | 13.3 | 21.4 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.6 | 7.3 | 14.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.8 | 1.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.8 | 1.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.8 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 29.1 | 30 | 28.6 |
| STAD | Stomach adenocarcinoma | 393 | 7.3 | 2.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 1.8 | 0.7 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 6.7 | 7.1 |