Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R699I | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E590D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I566I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L465F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L482F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L898L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M1016I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q606* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S842L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V950V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | W689* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | D1269N | Missense | 1 |
| BRCA | Breast invasive carcinoma | D367Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | L795P | Missense | 1 |
| BRCA | Breast invasive carcinoma | P519R | Missense | 1 |
| BRCA | Breast invasive carcinoma | P942S | Missense | 1 |
| COAD | Colon adenocarcinoma | E844K | Missense | 1 |
| COAD | Colon adenocarcinoma | I714I | Silent | 1 |
| COAD | Colon adenocarcinoma | L2L | Silent | 1 |
| COAD | Colon adenocarcinoma | P166L | Missense | 1 |
| COAD | Colon adenocarcinoma | P683P | Silent | 1 |
| COAD | Colon adenocarcinoma | P881H | Missense | 1 |
| COAD | Colon adenocarcinoma | R259Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R385* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R891K | Missense | 1 |
| COAD | Colon adenocarcinoma | S849S | Silent | 1 |
| COAD | Colon adenocarcinoma | V1284V | Silent | 1 |
| COAD | Colon adenocarcinoma | V322A | Missense | 1 |
| ESCA | Esophageal carcinoma | H848Y | Missense | 1 |
| ESCA | Esophageal carcinoma | K1106N | Missense | 1 |
| ESCA | Esophageal carcinoma | P166Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R385* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | S451F | Missense | 1 |
| ESCA | Esophageal carcinoma | V390E | Missense | 1 |
| GBM | Glioblastoma multiforme | Q1321P | Missense | 1 |
| GBM | Glioblastoma multiforme | R725* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | S1093P | Missense | 1 |
| GBM | Glioblastoma multiforme | V862I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H521R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S715L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C292S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G396D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P954L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S987Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T878M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G498G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L236L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S159G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T260A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T826I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V1276I | Missense | 1 |
| LUAD | Lung adenocarcinoma | G911* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H1055Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | I447I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1307I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P346L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P546Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1290S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V522V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E525Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E622E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q605E | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A763A | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R385* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | M638I | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | V665A | Missense | 1 |
| READ | Rectum adenocarcinoma | A1313A | Silent | 1 |
| READ | Rectum adenocarcinoma | R496H | Missense | 1 |
| READ | Rectum adenocarcinoma | R737Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D645N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D959Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1346K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E403E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G915E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1078F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L536W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L601F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1018L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1338S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P772L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1007* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R724G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T878K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1050I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1077V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V347V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V435V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W914* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A1319V | Missense | 1 |
| STAD | Stomach adenocarcinoma | I733T | Missense | 1 |
| STAD | Stomach adenocarcinoma | L630P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L787I | Missense | 1 |
| STAD | Stomach adenocarcinoma | N373S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P434S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R725Q | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q716* | Nonsense | 1 |
| THYM | Thymoma | A812V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1033V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1071A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A667T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1328S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C471S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1269N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D771G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1285K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1310E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E314D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1331T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L591F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L710S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R259Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R564H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R737* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R818L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R823I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T349N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1077I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V989A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14.3 | 5.7 | 18.2 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 23.8 | 6.9 | 9.1 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5.7 | 9.1 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.4 | 9.1 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 2.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 9.5 | 4.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.5 | 5.7 | 9.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.8 | 2.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 4.8 | 0 | 9.1 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.1 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 4.8 | 2.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 19 | 14.9 | 18.2 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 9.1 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 1.1 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.5 | 23 | 9.1 |