Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LAML | Acute Myeloid Leukemia | R1216* | Nonsense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1423V | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D768H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1106Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E330K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E628K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1090N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L426V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P989L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q35Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q417K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S466C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S509* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T691T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V449V | Silent | 1 |
| BRCA | Breast invasive carcinoma | C88C | Silent | 1 |
| BRCA | Breast invasive carcinoma | D1384H | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1694S | Missense | 1 |
| BRCA | Breast invasive carcinoma | L426V | Missense | 1 |
| BRCA | Breast invasive carcinoma | P656S | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q1603* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S1369L | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1593N | Missense | 1 |
| BRCA | Breast invasive carcinoma | S716L | Missense | 1 |
| CESC | Cervical and endocervical cancers | H762Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | I1024M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1048L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L1240L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L1531V | Missense | 1 |
| CESC | Cervical and endocervical cancers | P761A | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1359C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S736* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A277T | Missense | 1 |
| COAD | Colon adenocarcinoma | A347V | Missense | 1 |
| COAD | Colon adenocarcinoma | F797F | Silent | 1 |
| COAD | Colon adenocarcinoma | H1036H | Silent | 1 |
| COAD | Colon adenocarcinoma | H880R | Missense | 1 |
| COAD | Colon adenocarcinoma | H994R | Missense | 1 |
| COAD | Colon adenocarcinoma | L956I | Missense | 1 |
| COAD | Colon adenocarcinoma | N1403S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1435H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1451Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1974M | Missense | 1 |
| COAD | Colon adenocarcinoma | R544* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S1691A | Missense | 1 |
| COAD | Colon adenocarcinoma | S1944F | Missense | 1 |
| COAD | Colon adenocarcinoma | S696S | Silent | 1 |
| COAD | Colon adenocarcinoma | T1149T | Silent | 1 |
| COAD | Colon adenocarcinoma | T27I | Missense | 1 |
| COAD | Colon adenocarcinoma | V1180G | Missense | 1 |
| ESCA | Esophageal carcinoma | C1378Y | Missense | 1 |
| ESCA | Esophageal carcinoma | D666D | Silent | 1 |
| ESCA | Esophageal carcinoma | G1861R | Missense | 1 |
| ESCA | Esophageal carcinoma | L694R | Missense | 1 |
| ESCA | Esophageal carcinoma | N1748S | Missense | 1 |
| ESCA | Esophageal carcinoma | Q866K | Missense | 1 |
| ESCA | Esophageal carcinoma | Q892Q | Silent | 1 |
| ESCA | Esophageal carcinoma | S217S | Silent | 1 |
| ESCA | Esophageal carcinoma | T1251M | Missense | 1 |
| ESCA | Esophageal carcinoma | V242L | Missense | 1 |
| GBM | Glioblastoma multiforme | K982N | Missense | 1 |
| GBM | Glioblastoma multiforme | S268A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1037A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E503E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G563* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G908C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I981I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1052R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P739H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q831* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R550* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R771K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S588* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T443T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | D194E | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K326* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L757V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N1390H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N1714K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q317K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1451Q | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V449E | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E788* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | F316I | Missense | 1 |
| LAML | Acute Myeloid Leukemia | A1863D | Missense | 1 |
| LAML | Acute Myeloid Leukemia | E1352V | Missense | 1 |
| LAML | Acute Myeloid Leukemia | H1868Y | Missense | 1 |
| LAML | Acute Myeloid Leukemia | P1889L | Missense | 1 |
| LAML | Acute Myeloid Leukemia | Q481* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | Q916* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | Q947* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R1452* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R1516* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R550* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | D932G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L579V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P23S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R686* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | V198I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H169L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H864H | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R1201C | Missense | 1 |
| LUAD | Lung adenocarcinoma | D299N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E100* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E1057* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E130Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G364V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L112L | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1680Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R534T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T497S | Missense | 1 |
| LUAD | Lung adenocarcinoma | T838A | Missense | 1 |
| LUAD | Lung adenocarcinoma | V242L | Missense | 1 |
| LUAD | Lung adenocarcinoma | W954S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E10Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P942S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q108Q | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R123S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S75C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P732Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C677* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | F125F | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | K111* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | L590I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A347V | Missense | 1 |
| READ | Rectum adenocarcinoma | E524E | Silent | 1 |
| READ | Rectum adenocarcinoma | E782* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | F797F | Silent | 1 |
| READ | Rectum adenocarcinoma | L1101I | Missense | 1 |
| READ | Rectum adenocarcinoma | P474P | Silent | 1 |
| READ | Rectum adenocarcinoma | S142S | Silent | 1 |
| SARC | Sarcoma | C1709Y | Missense | 1 |
| SARC | Sarcoma | L1065F | Missense | 1 |
| SARC | Sarcoma | R1712K | Missense | 1 |
| SARC | Sarcoma | S1820T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A727T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E320K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G105R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G92R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H682Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H762Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K1008K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K1094I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N488S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P16L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P16S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P408L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P465L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P474L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P474S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P763P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q958Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S15I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S239S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S268L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S327L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S391S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T1069A | Missense | 1 |
| STAD | Stomach adenocarcinoma | A569V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C25F | Missense | 1 |
| STAD | Stomach adenocarcinoma | E186E | Silent | 1 |
| STAD | Stomach adenocarcinoma | H511R | Missense | 1 |
| STAD | Stomach adenocarcinoma | H661R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L405R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L748I | Missense | 1 |
| STAD | Stomach adenocarcinoma | S137T | Missense | 1 |
| STAD | Stomach adenocarcinoma | S384G | Missense | 1 |
| STAD | Stomach adenocarcinoma | S393A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1122T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T279P | Missense | 1 |
| STAD | Stomach adenocarcinoma | V698V | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y437C | Missense | 1 |
| THCA | Thyroid carcinoma | I340M | Missense | 1 |
| THYM | Thymoma | C1378R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1350Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E433E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E81* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F125F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F797F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1229I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L525I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L956I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N275S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1655P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P474L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q324H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R544* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R544R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R550Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R581C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R680G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R814H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1015S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1611Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T759N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T779T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T849I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1846V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y1589Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.7 | 6.9 | 3.8 |
| BRCA | Breast invasive carcinoma | 976 | 2.2 | 5.4 | 3.8 |
| CESC | Cervical and endocervical cancers | 194 | 4.4 | 3.8 | 3.8 |
| COAD | Colon adenocarcinoma | 367 | 8.9 | 10 | 3.8 |
| ESCA | Esophageal carcinoma | 185 | 6.7 | 5.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.9 | 3.1 | 15.4 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 5.4 | 3.8 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 3.8 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 3.1 | 30.8 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.1 | 3.8 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.2 | 1.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.4 | 6.2 | 7.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.2 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.2 | 0.8 | 7.7 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 8.9 | 0.8 | 3.8 |
| SARC | Sarcoma | 247 | 0 | 3.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.1 | 13.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 6.7 | 8.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0.8 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 24.4 | 10.8 | 7.7 |