Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R1658H | Missense | 3 |
| STAD | Stomach adenocarcinoma | Y1144Y | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A1389D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E109K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1591E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E973K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1606G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K623N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M132I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q195H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q206H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1027W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1142C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1505S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V159V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Y1647C | Missense | 1 |
| BRCA | Breast invasive carcinoma | E580D | Missense | 1 |
| BRCA | Breast invasive carcinoma | E87Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1395L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L59L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L660L | Silent | 1 |
| BRCA | Breast invasive carcinoma | T242N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E912K | Missense | 1 |
| CESC | Cervical and endocervical cancers | F886L | Missense | 1 |
| CESC | Cervical and endocervical cancers | L173M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L189F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S618S | Silent | 1 |
| COAD | Colon adenocarcinoma | A62V | Missense | 1 |
| COAD | Colon adenocarcinoma | D323N | Missense | 1 |
| COAD | Colon adenocarcinoma | D585N | Missense | 1 |
| COAD | Colon adenocarcinoma | E278E | Silent | 1 |
| COAD | Colon adenocarcinoma | E406Q | Missense | 1 |
| COAD | Colon adenocarcinoma | G1306G | Silent | 1 |
| COAD | Colon adenocarcinoma | G1654D | Missense | 1 |
| COAD | Colon adenocarcinoma | L1512L | Silent | 1 |
| COAD | Colon adenocarcinoma | N963S | Missense | 1 |
| COAD | Colon adenocarcinoma | P512H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1374* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R798H | Missense | 1 |
| COAD | Colon adenocarcinoma | R926W | Missense | 1 |
| COAD | Colon adenocarcinoma | R964C | Missense | 1 |
| COAD | Colon adenocarcinoma | S1121S | Silent | 1 |
| COAD | Colon adenocarcinoma | S210N | Missense | 1 |
| COAD | Colon adenocarcinoma | V966M | Missense | 1 |
| ESCA | Esophageal carcinoma | A1434V | Missense | 1 |
| ESCA | Esophageal carcinoma | G1606R | Missense | 1 |
| ESCA | Esophageal carcinoma | L542L | Silent | 1 |
| ESCA | Esophageal carcinoma | P1087P | Silent | 1 |
| ESCA | Esophageal carcinoma | P1211P | Silent | 1 |
| ESCA | Esophageal carcinoma | P324S | Missense | 1 |
| ESCA | Esophageal carcinoma | Q506* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | S627S | Silent | 1 |
| GBM | Glioblastoma multiforme | P1359P | Silent | 1 |
| GBM | Glioblastoma multiforme | P364S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A933D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A97S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1455K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P419P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q244L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q506* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S115R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V954M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G1405W | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G930G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E375D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P590P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R490* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | V717V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | A1520A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L219L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q1208L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R538S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S239C | Missense | 1 |
| LUAD | Lung adenocarcinoma | F1558L | Missense | 1 |
| LUAD | Lung adenocarcinoma | F259F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G1384V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I741I | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1529L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P194R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P248A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P377L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q263* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R919C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S369F | Missense | 1 |
| LUAD | Lung adenocarcinoma | S852I | Missense | 1 |
| LUAD | Lung adenocarcinoma | V75L | Missense | 1 |
| LUAD | Lung adenocarcinoma | W47S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A1214V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G29A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S634S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T716T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | W1321C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R1658C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A126T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A872T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K443M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A718T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K446Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P1159P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P1377P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R1594W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T1135I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T1541M | Missense | 1 |
| READ | Rectum adenocarcinoma | E1590G | Missense | 1 |
| READ | Rectum adenocarcinoma | P1359P | Silent | 1 |
| READ | Rectum adenocarcinoma | Q394K | Missense | 1 |
| READ | Rectum adenocarcinoma | R1374Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R577Q | Missense | 1 |
| READ | Rectum adenocarcinoma | T1541T | Silent | 1 |
| SARC | Sarcoma | A227V | Missense | 1 |
| SARC | Sarcoma | E807K | Missense | 1 |
| SARC | Sarcoma | P927L | Missense | 1 |
| SARC | Sarcoma | P979L | Missense | 1 |
| SARC | Sarcoma | R12R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A301T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1289E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1459R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I737I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K213K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1017L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1240L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1395Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1249P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1393S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P248L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P275L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P316P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P346L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P366L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P370S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P509S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P536P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P566S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P590S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P970L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R862W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R870C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1093S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S112F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1260F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1325L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S369S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S412S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W271* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A1214T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A67A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A872T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C831C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D384N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1289K | Missense | 1 |
| STAD | Stomach adenocarcinoma | I1516I | Silent | 1 |
| STAD | Stomach adenocarcinoma | L1007P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1440L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L711L | Silent | 1 |
| STAD | Stomach adenocarcinoma | M853V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P104L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R129R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1588W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R40Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R862W | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1541M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T743M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y1197Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S749I | Missense | 1 |
| THCA | Thyroid carcinoma | H710Y | Missense | 1 |
| THCA | Thyroid carcinoma | P250P | Silent | 1 |
| THYM | Thymoma | R401C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1009V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A929T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1019K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E347G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E689K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F937V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K44T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1276S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q195Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R129R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1372W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1097S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1409L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7 | 8.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.3 | 2.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 1.8 | 3.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7 | 12.5 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 7 | 2.5 | 16.7 |
| GBM | Glioblastoma multiforme | 283 | 1.8 | 0.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 1.8 | 5 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.8 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.5 | 0.8 | 16.7 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.5 | 2.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.3 | 8.3 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.5 | 2.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.5 | 4.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.5 | 3.3 | 0 |
| SARC | Sarcoma | 247 | 1.8 | 3.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 19.3 | 15 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 15.8 | 10 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 1.8 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0.8 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.3 | 8.3 | 0 |