Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | D1738D | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A2902A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | A520T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D706Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1375K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E2952K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1609I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L2274L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L2296V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L2427L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L739L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P1173L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1100* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q148E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R2752T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1812Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S2694F | Missense | 1 |
| BRCA | Breast invasive carcinoma | A2084T | Missense | 1 |
| BRCA | Breast invasive carcinoma | A784V | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1397Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E2555K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G2594C | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1555L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L1788L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L2251L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P2136S | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1486Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1579F | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1651T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S2629S | Silent | 1 |
| BRCA | Breast invasive carcinoma | S903* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | A1570V | Missense | 1 |
| CESC | Cervical and endocervical cancers | D2155G | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1171D | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1404D | Missense | 1 |
| CESC | Cervical and endocervical cancers | P2225Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1484W | Missense | 1 |
| CESC | Cervical and endocervical cancers | R2048K | Missense | 1 |
| CESC | Cervical and endocervical cancers | S792F | Missense | 1 |
| COAD | Colon adenocarcinoma | A1242T | Missense | 1 |
| COAD | Colon adenocarcinoma | A1535T | Missense | 1 |
| COAD | Colon adenocarcinoma | A944T | Missense | 1 |
| COAD | Colon adenocarcinoma | D1670N | Missense | 1 |
| COAD | Colon adenocarcinoma | D1744D | Silent | 1 |
| COAD | Colon adenocarcinoma | D1815N | Missense | 1 |
| COAD | Colon adenocarcinoma | D2910D | Silent | 1 |
| COAD | Colon adenocarcinoma | E2942D | Missense | 1 |
| COAD | Colon adenocarcinoma | G1435G | Silent | 1 |
| COAD | Colon adenocarcinoma | G2267R | Missense | 1 |
| COAD | Colon adenocarcinoma | K1544R | Missense | 1 |
| COAD | Colon adenocarcinoma | L1539M | Missense | 1 |
| COAD | Colon adenocarcinoma | L1782M | Missense | 1 |
| COAD | Colon adenocarcinoma | L2947L | Silent | 1 |
| COAD | Colon adenocarcinoma | P120H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1445Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1514R | Silent | 1 |
| COAD | Colon adenocarcinoma | R2035C | Missense | 1 |
| COAD | Colon adenocarcinoma | R2040C | Missense | 1 |
| COAD | Colon adenocarcinoma | R2330S | Missense | 1 |
| COAD | Colon adenocarcinoma | S2565S | Silent | 1 |
| COAD | Colon adenocarcinoma | S2664P | Missense | 1 |
| COAD | Colon adenocarcinoma | S2918S | Silent | 1 |
| COAD | Colon adenocarcinoma | S80L | Missense | 1 |
| ESCA | Esophageal carcinoma | G969G | Silent | 1 |
| ESCA | Esophageal carcinoma | L119M | Missense | 1 |
| ESCA | Esophageal carcinoma | L1756L | Silent | 1 |
| ESCA | Esophageal carcinoma | L700L | Silent | 1 |
| ESCA | Esophageal carcinoma | P1128P | Silent | 1 |
| ESCA | Esophageal carcinoma | P1251P | Silent | 1 |
| ESCA | Esophageal carcinoma | P2391L | Missense | 1 |
| ESCA | Esophageal carcinoma | R1486W | Missense | 1 |
| ESCA | Esophageal carcinoma | S1644L | Missense | 1 |
| ESCA | Esophageal carcinoma | S2882I | Missense | 1 |
| GBM | Glioblastoma multiforme | R734W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1809A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1057K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E2459E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G505G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1175V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1245L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P2487L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P2862P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P681L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1248K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R734Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1217F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T521T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1247V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A1783A | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A2830A | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G1660G | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L107P | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V2917A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K960N | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S2632S | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S2713L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K1455N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1333R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R1573R | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1951H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R2798H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S2907L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y2188* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | A584V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D1640G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D2465E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E1834V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G2267A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K620E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L1636L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q1381P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1817S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S2563S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S2569G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S2629S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S2658S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Y591F | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1193A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1176* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G1301V | Missense | 1 |
| LUAD | Lung adenocarcinoma | H1602R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P498P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q2207* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | Q2237R | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1145L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R2196P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R666L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S2713S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T2269T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V1270M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A2723A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A2780S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D2268Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D2878N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1745* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | K2719M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1775L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P2451T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R2452Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A832T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G1364A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A2703S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E134E | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R1507H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R2890Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E2133K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L1074M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P2361L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R2840H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R603C | Missense | 1 |
| READ | Rectum adenocarcinoma | D2120G | Missense | 1 |
| READ | Rectum adenocarcinoma | K1617N | Missense | 1 |
| SARC | Sarcoma | A1478V | Missense | 1 |
| SARC | Sarcoma | A2697V | Missense | 1 |
| SARC | Sarcoma | A2902T | Missense | 1 |
| SARC | Sarcoma | A539V | Missense | 1 |
| SARC | Sarcoma | E1736K | Missense | 1 |
| SARC | Sarcoma | R2383* | Nonsense | 1 |
| SARC | Sarcoma | R721L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A2804A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A689A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D2258D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D2283D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F1331F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F1813F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F2781F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G162R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1781S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K2869T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1043S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1121L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1238L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1269L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P205L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P702S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1623* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q2873Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1134R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1780R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R2805C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R690W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1820L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1104A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1585V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A2695V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A2779A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A528V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1738D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1129K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E676D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F2791F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G2468D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G2718C | Missense | 1 |
| STAD | Stomach adenocarcinoma | G2815G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G2822R | Missense | 1 |
| STAD | Stomach adenocarcinoma | I2841I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K1923E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L2279I | Missense | 1 |
| STAD | Stomach adenocarcinoma | N2774S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1089P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1143P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1251P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1645P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P2731L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P879P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q1493R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1156W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1532Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1931Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R2137C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R2302C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R2840C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R636C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R709C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1285R | Missense | 1 |
| STAD | Stomach adenocarcinoma | S2907S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S2918S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T780M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A2076T | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | E1740K | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G698D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P1148P | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S2563S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | T242I | Missense | 1 |
| THCA | Thyroid carcinoma | G1578R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A112T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1394T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A2780T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A2948A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1213C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1292* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1739D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E2536K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1689N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1710Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K2098N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1040L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P2064P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1448W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1543H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2137C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2189R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2239H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1820L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S2621S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S2677Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S84N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V86V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.5 | 6.1 | 11.1 |
| BRCA | Breast invasive carcinoma | 976 | 5.2 | 5.5 | 11.1 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.7 | 10.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.5 | 3.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.1 | 4.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.9 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.3 | 1.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.3 | 3.1 | 11.1 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.5 | 5.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.2 | 4.3 | 22.2 |
| LUSC | Lung squamous cell carcinoma | 177 | 1.3 | 4.3 | 11.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.3 | 1.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.7 | 11.1 |
| SKCM | Skin Cutaneous Melanoma | 290 | 13 | 7.4 | 11.1 |
| STAD | Stomach adenocarcinoma | 393 | 16.9 | 14.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.6 | 2.5 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.8 | 9.8 | 11.1 |