Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E55* | Nonsense | 2 |
| LIHC | Liver hepatocellular carcinoma | P561R | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A90S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1075Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1165K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1551K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E260G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G122G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G1720W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G676A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G976R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I104F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I104M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I914I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | N1188S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1636S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P843A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P903S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q106K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q113K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q14* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q26* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1049Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1132W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1338K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S862S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S888C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T117I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y1515S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1573Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E773D | Missense | 1 |
| BRCA | Breast invasive carcinoma | F1816F | Silent | 1 |
| BRCA | Breast invasive carcinoma | G1783A | Missense | 1 |
| BRCA | Breast invasive carcinoma | I1617S | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1161F | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1817L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L1875L | Silent | 1 |
| BRCA | Breast invasive carcinoma | M648V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q729E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1668I | Missense | 1 |
| BRCA | Breast invasive carcinoma | R206W | Missense | 1 |
| BRCA | Breast invasive carcinoma | R348K | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1665L | Missense | 1 |
| BRCA | Breast invasive carcinoma | S635F | Missense | 1 |
| BRCA | Breast invasive carcinoma | S937S | Silent | 1 |
| BRCA | Breast invasive carcinoma | V1487I | Missense | 1 |
| BRCA | Breast invasive carcinoma | V1558G | Missense | 1 |
| BRCA | Breast invasive carcinoma | V363F | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y1815C | Missense | 1 |
| CESC | Cervical and endocervical cancers | A879T | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1126Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | F12F | Silent | 1 |
| CESC | Cervical and endocervical cancers | M989I | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q106E | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1811Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | S452C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S755I | Missense | 1 |
| CESC | Cervical and endocervical cancers | T1740A | Missense | 1 |
| COAD | Colon adenocarcinoma | A1733T | Missense | 1 |
| COAD | Colon adenocarcinoma | D149Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D1923G | Missense | 1 |
| COAD | Colon adenocarcinoma | E1073D | Missense | 1 |
| COAD | Colon adenocarcinoma | E1575* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E663G | Missense | 1 |
| COAD | Colon adenocarcinoma | E799D | Missense | 1 |
| COAD | Colon adenocarcinoma | F1501V | Missense | 1 |
| COAD | Colon adenocarcinoma | P1963L | Missense | 1 |
| COAD | Colon adenocarcinoma | P254P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q832Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R1049Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1247H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1668I | Missense | 1 |
| COAD | Colon adenocarcinoma | R1781Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S1202S | Silent | 1 |
| COAD | Colon adenocarcinoma | S1326N | Missense | 1 |
| COAD | Colon adenocarcinoma | S1430P | Missense | 1 |
| COAD | Colon adenocarcinoma | T52T | Silent | 1 |
| COAD | Colon adenocarcinoma | Y1523Y | Silent | 1 |
| ESCA | Esophageal carcinoma | E608* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | M684L | Missense | 1 |
| ESCA | Esophageal carcinoma | P688T | Missense | 1 |
| ESCA | Esophageal carcinoma | Q1220K | Missense | 1 |
| ESCA | Esophageal carcinoma | Q1938* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | E657E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D589H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E109* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1266K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1760K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1855K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E418K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E646* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G969G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I1039M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1611V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L844S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P381S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q241Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q51R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1252H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1747S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1971F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S660L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T382T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S867* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S877* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S975F | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E219E | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L1217L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | M551L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P263P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q852* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S1354C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E1274* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | I1859V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R1684H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V1124V | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1145K | Missense | 1 |
| LUAD | Lung adenocarcinoma | F1771L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1079C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1472V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G969G | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1540Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L508F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1112L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P688S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q231L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q231Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q292* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R594G | Missense | 1 |
| LUAD | Lung adenocarcinoma | S490F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G1343W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q406* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | S1665* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | S287I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T1173S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Y1523* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | M1157R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1231L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P254S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K1726T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1396H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S1589P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1607T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A998V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I376I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | K680* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | Q573H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1238H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1811* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | R1844H | Missense | 1 |
| READ | Rectum adenocarcinoma | D1451Y | Missense | 1 |
| READ | Rectum adenocarcinoma | E224K | Missense | 1 |
| READ | Rectum adenocarcinoma | E283* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E737* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E911* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R1238C | Missense | 1 |
| READ | Rectum adenocarcinoma | R1241I | Missense | 1 |
| READ | Rectum adenocarcinoma | R1583L | Missense | 1 |
| READ | Rectum adenocarcinoma | R1811Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R767I | Missense | 1 |
| SARC | Sarcoma | D539E | Missense | 1 |
| SARC | Sarcoma | L350L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1454A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D1743A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D1743Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E549K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F443F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G971E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G971G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H39H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H653H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H654Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1243I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K293M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K972N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1321F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L506L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1466S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1702S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P335S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P550S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P561S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P668S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P764L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1396C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1400Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R634* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1306F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S157S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1701S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S452S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S483L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S754F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S784S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S834F | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1301A | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1117E | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1504W | Missense | 1 |
| STAD | Stomach adenocarcinoma | L679H | Missense | 1 |
| STAD | Stomach adenocarcinoma | L679P | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1355* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1438S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1459H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1684H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1748C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R767K | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1019T | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1101Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1140S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1310P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S63S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V1544M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1663I | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y1843C | Missense | 1 |
| THCA | Thyroid carcinoma | E962E | Silent | 1 |
| THCA | Thyroid carcinoma | G976W | Missense | 1 |
| THCA | Thyroid carcinoma | S1446S | Silent | 1 |
| THYM | Thymoma | R1355R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1641T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1001* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E138* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E224K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E251* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E737* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E86* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G5E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1819F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L555V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N582N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1657L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P629P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1442* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1578I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1668I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1684C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1342S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S359Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y1523Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.5 | 13.4 | 6.7 |
| BRCA | Breast invasive carcinoma | 976 | 8.7 | 9.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.2 | 4.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.9 | 8.5 | 10 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.8 | 6.7 |
| GBM | Glioblastoma multiforme | 283 | 2.2 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.7 | 7.9 | 6.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0.6 | 6.7 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 6.5 | 1.2 | 3.3 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.2 | 3.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.2 | 1.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.3 | 6.7 | 3.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.8 | 10 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.2 | 3 | 6.7 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.3 | 10 |
| SARC | Sarcoma | 247 | 2.2 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.9 | 12.8 | 3.3 |
| STAD | Stomach adenocarcinoma | 393 | 4.3 | 9.8 | 3.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 4.3 | 0.6 | 0 |
| THYM | Thymoma | 119 | 2.2 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.7 | 6.1 | 20 |