Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | T577A | Missense | 4 |
| COAD | Colon adenocarcinoma | K1002R | Missense | 2 |
| COAD | Colon adenocarcinoma | R391R | Silent | 2 |
| COAD | Colon adenocarcinoma | R721* | Nonsense | 2 |
| COAD | Colon adenocarcinoma | S957S | Silent | 2 |
| ESCA | Esophageal carcinoma | A135V | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P460S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C187S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D781N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D872H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E136E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E136K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E150K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E994Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H226Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M340I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M498V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q64R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1046C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R721Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S618S | Silent | 1 |
| BRCA | Breast invasive carcinoma | A135G | Missense | 1 |
| BRCA | Breast invasive carcinoma | I1043V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1001V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L277L | Silent | 1 |
| BRCA | Breast invasive carcinoma | N265I | Missense | 1 |
| BRCA | Breast invasive carcinoma | P533H | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q218* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q544H | Missense | 1 |
| COAD | Colon adenocarcinoma | C844Y | Missense | 1 |
| COAD | Colon adenocarcinoma | G214V | Missense | 1 |
| COAD | Colon adenocarcinoma | I425I | Silent | 1 |
| COAD | Colon adenocarcinoma | I683M | Missense | 1 |
| COAD | Colon adenocarcinoma | P1035L | Missense | 1 |
| COAD | Colon adenocarcinoma | P447S | Missense | 1 |
| COAD | Colon adenocarcinoma | R126C | Missense | 1 |
| COAD | Colon adenocarcinoma | R219* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R339C | Missense | 1 |
| COAD | Colon adenocarcinoma | R391C | Missense | 1 |
| COAD | Colon adenocarcinoma | S957P | Missense | 1 |
| COAD | Colon adenocarcinoma | T403A | Missense | 1 |
| ESCA | Esophageal carcinoma | D968Y | Missense | 1 |
| ESCA | Esophageal carcinoma | P128S | Missense | 1 |
| ESCA | Esophageal carcinoma | R819K | Missense | 1 |
| ESCA | Esophageal carcinoma | T592T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1031N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E429D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E864E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I270V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q563K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S430C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V399V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | I866L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L945F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1047H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A47A | Silent | 1 |
| LAML | Acute Myeloid Leukemia | R910C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E978K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G695E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N543N | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R339H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y755Y | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R486Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | D806Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E429D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E842G | Missense | 1 |
| LUAD | Lung adenocarcinoma | K146K | Silent | 1 |
| LUAD | Lung adenocarcinoma | K146N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K354E | Missense | 1 |
| LUAD | Lung adenocarcinoma | L857F | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q557Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R339C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S771C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V180F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E895K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P513P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P625L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S663S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | K1002N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V679V | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | E426K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R469W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P39P | Silent | 1 |
| READ | Rectum adenocarcinoma | K198K | Silent | 1 |
| READ | Rectum adenocarcinoma | P719S | Missense | 1 |
| READ | Rectum adenocarcinoma | R721* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | S957S | Silent | 1 |
| READ | Rectum adenocarcinoma | T403P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E743K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F459F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G492G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I417I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K146Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P439S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P512L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P625L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1036W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S397S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S585F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S762F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S957S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A559V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C130C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E999K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G500G | Silent | 1 |
| STAD | Stomach adenocarcinoma | L273L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P885S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1046H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R339H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R385W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S65N | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C908F | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q446* | Nonsense | 1 |
| THCA | Thyroid carcinoma | S667F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P432P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R469Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R684C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R721* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T592M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.5 | 13.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.2 | 5.6 | 14.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.1 | 17.8 | 42.9 |
| ESCA | Esophageal carcinoma | 185 | 3.2 | 5.6 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.5 | 5.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.2 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1.1 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.5 | 3.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.5 | 10 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.5 | 2.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.2 | 1.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.2 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.5 | 2.2 | 14.3 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.1 | 11.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.7 | 7.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.1 | 14.3 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.2 | 3.3 | 14.3 |