Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D1050H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F415F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G578R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L439L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q317E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T218T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V387L | Missense | 1 |
| BRCA | Breast invasive carcinoma | C975R | Missense | 1 |
| BRCA | Breast invasive carcinoma | E977* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | Q1064* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | Q190H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R185C | Missense | 1 |
| BRCA | Breast invasive carcinoma | R446R | Silent | 1 |
| CESC | Cervical and endocervical cancers | E1121D | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q538K | Missense | 1 |
| COAD | Colon adenocarcinoma | A328A | Silent | 1 |
| COAD | Colon adenocarcinoma | A955V | Missense | 1 |
| COAD | Colon adenocarcinoma | E811D | Missense | 1 |
| COAD | Colon adenocarcinoma | E811G | Missense | 1 |
| COAD | Colon adenocarcinoma | G896R | Missense | 1 |
| COAD | Colon adenocarcinoma | I402T | Missense | 1 |
| COAD | Colon adenocarcinoma | K249N | Missense | 1 |
| COAD | Colon adenocarcinoma | L326L | Silent | 1 |
| COAD | Colon adenocarcinoma | M580T | Missense | 1 |
| COAD | Colon adenocarcinoma | M580V | Missense | 1 |
| COAD | Colon adenocarcinoma | P885S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q345Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R272H | Missense | 1 |
| COAD | Colon adenocarcinoma | R865* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T1085A | Missense | 1 |
| COAD | Colon adenocarcinoma | Y994C | Missense | 1 |
| ESCA | Esophageal carcinoma | A445E | Missense | 1 |
| ESCA | Esophageal carcinoma | A584D | Missense | 1 |
| ESCA | Esophageal carcinoma | I179R | Missense | 1 |
| GBM | Glioblastoma multiforme | R440H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E811Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N652I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P488S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q586E | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H869Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S263* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T1005T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | V491I | Missense | 1 |
| LUAD | Lung adenocarcinoma | A593T | Missense | 1 |
| LUAD | Lung adenocarcinoma | C902S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D448D | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1091D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E324D | Missense | 1 |
| LUAD | Lung adenocarcinoma | F1109F | Silent | 1 |
| LUAD | Lung adenocarcinoma | M1042I | Missense | 1 |
| LUAD | Lung adenocarcinoma | M393I | Missense | 1 |
| LUAD | Lung adenocarcinoma | M845T | Missense | 1 |
| LUAD | Lung adenocarcinoma | P463S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1113H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A804A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G455A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S406S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V409V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | L822V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P603S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L516I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q513Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S871L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A891V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | C238Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | C928C | Silent | 1 |
| PRAD | Prostate adenocarcinoma | F287F | Silent | 1 |
| PRAD | Prostate adenocarcinoma | Q552Q | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R1029C | Missense | 1 |
| READ | Rectum adenocarcinoma | E1079D | Missense | 1 |
| READ | Rectum adenocarcinoma | E967G | Missense | 1 |
| READ | Rectum adenocarcinoma | G270A | Missense | 1 |
| READ | Rectum adenocarcinoma | H518N | Missense | 1 |
| READ | Rectum adenocarcinoma | P885Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E372* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | I256I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1089L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L700L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R407G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R655G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1028V | Silent | 1 |
| STAD | Stomach adenocarcinoma | N335K | Missense | 1 |
| STAD | Stomach adenocarcinoma | N489I | Missense | 1 |
| STAD | Stomach adenocarcinoma | R180Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R185H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R446Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R458C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S644N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1078A | Missense | 1 |
| THCA | Thyroid carcinoma | L696F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A328A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A955A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1108Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E940* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H869Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1033N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K904Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L429L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P624S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1094R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R391I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R865* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R968H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S679S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S694N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1078I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1006M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V274I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V351V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V939D | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.5 | 5.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.8 | 3.9 | 28.6 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.5 | 15.6 | 14.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.3 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 5.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.8 | 1.3 | 14.3 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 11.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 11.5 | 1.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.8 | 2.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 11.5 | 3.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 6.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 2.6 | 14.3 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.4 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.3 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 19.2 | 16.9 | 28.6 |