Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A412A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D130N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E198Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E852* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | H1082N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H116Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L717L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L923L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L930V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N706K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P23P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1062* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1062E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q264E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S864* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | A136A | Silent | 1 |
| BRCA | Breast invasive carcinoma | G327A | Missense | 1 |
| BRCA | Breast invasive carcinoma | G544S | Missense | 1 |
| BRCA | Breast invasive carcinoma | L609L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L893L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L917L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q276H | Missense | 1 |
| BRCA | Breast invasive carcinoma | S908S | Silent | 1 |
| CESC | Cervical and endocervical cancers | E238K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L550L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L652L | Silent | 1 |
| CESC | Cervical and endocervical cancers | Q1017* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q133E | Missense | 1 |
| CESC | Cervical and endocervical cancers | S908* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | W138L | Missense | 1 |
| COAD | Colon adenocarcinoma | A206T | Missense | 1 |
| COAD | Colon adenocarcinoma | A329A | Silent | 1 |
| COAD | Colon adenocarcinoma | D353D | Silent | 1 |
| COAD | Colon adenocarcinoma | F163F | Silent | 1 |
| COAD | Colon adenocarcinoma | G976D | Missense | 1 |
| COAD | Colon adenocarcinoma | H531H | Silent | 1 |
| COAD | Colon adenocarcinoma | L958L | Silent | 1 |
| COAD | Colon adenocarcinoma | L958S | Missense | 1 |
| COAD | Colon adenocarcinoma | N1091K | Missense | 1 |
| COAD | Colon adenocarcinoma | P486H | Missense | 1 |
| COAD | Colon adenocarcinoma | P884H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q109H | Missense | 1 |
| ESCA | Esophageal carcinoma | E852D | Missense | 1 |
| ESCA | Esophageal carcinoma | S912I | Missense | 1 |
| GBM | Glioblastoma multiforme | A1037V | Missense | 1 |
| GBM | Glioblastoma multiforme | E284E | Silent | 1 |
| GBM | Glioblastoma multiforme | V19V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A998G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D597N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F386F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I1162I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K468N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K624* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P317L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R728Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S723* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1101Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I447M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | H654Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A1098S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I301L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S889G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T1121T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A579D | Missense | 1 |
| LUAD | Lung adenocarcinoma | D352G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E661* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G599A | Missense | 1 |
| LUAD | Lung adenocarcinoma | G62C | Missense | 1 |
| LUAD | Lung adenocarcinoma | H642H | Silent | 1 |
| LUAD | Lung adenocarcinoma | P492L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P836P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q493Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R784L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R890K | Missense | 1 |
| LUAD | Lung adenocarcinoma | T458T | Silent | 1 |
| LUAD | Lung adenocarcinoma | W94C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K814R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L717L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | N771S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q770R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L958F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T694S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q446H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G485G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R746Q | Missense | 1 |
| READ | Rectum adenocarcinoma | L1141I | Missense | 1 |
| READ | Rectum adenocarcinoma | L783I | Missense | 1 |
| READ | Rectum adenocarcinoma | R80I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A760A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F163F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I691I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1159F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N665D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P437L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P836P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S970F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S973F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S973S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T380R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y416Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | A398A | Silent | 1 |
| STAD | Stomach adenocarcinoma | D164N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D215N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D907V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E807G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E941A | Missense | 1 |
| STAD | Stomach adenocarcinoma | G342G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K701N | Missense | 1 |
| STAD | Stomach adenocarcinoma | R413W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R497H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R548H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R663W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R733Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R838H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S641P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T813A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1105I | Missense | 1 |
| STAD | Stomach adenocarcinoma | W288L | Missense | 1 |
| THCA | Thyroid carcinoma | G601E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A752D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D638D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E193* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G62D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H110Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1127V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L15I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L261P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L955I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R524Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S244R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S374S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S778S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V854A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 10.5 | 9.3 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 13.2 | 3.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.3 | 3.5 | 22.2 |
| COAD | Colon adenocarcinoma | 367 | 13.2 | 8.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 5.3 | 1.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.3 | 5.8 | 22.2 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.6 | 3.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 10.5 | 9.3 | 11.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.6 | 3.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.6 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.8 | 7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.3 | 18.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.2 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.9 | 11.6 | 11.1 |