Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BRCA | Breast invasive carcinoma | D333D | Silent | 1 |
| BRCA | Breast invasive carcinoma | R98C | Missense | 1 |
| COAD | Colon adenocarcinoma | A280T | Missense | 1 |
| COAD | Colon adenocarcinoma | L387L | Silent | 1 |
| COAD | Colon adenocarcinoma | R213Q | Missense | 1 |
| COAD | Colon adenocarcinoma | V157D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R416T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V251I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P142S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A391V | Missense | 1 |
| LUAD | Lung adenocarcinoma | K245K | Silent | 1 |
| LUAD | Lung adenocarcinoma | K274N | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q295H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q349* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | A261A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D336Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G229V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K54K | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L114F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L372L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Y126Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | E230E | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R213Q | Missense | 1 |
| READ | Rectum adenocarcinoma | C155C | Silent | 1 |
| READ | Rectum adenocarcinoma | P142A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L236L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P306P | Silent | 1 |
| STAD | Stomach adenocarcinoma | D336N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T93A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D300E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E342* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K225K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N127D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q349H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R213Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V338I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 4.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 8.3 | 13.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 9.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.3 | 13.6 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 25 | 13.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 8.3 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 8.3 | 4.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 8.3 | 4.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.7 | 0 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 9.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.3 | 22.7 | 50 |