Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E1087G | Missense | 3 |
| STAD | Stomach adenocarcinoma | R729C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | H263Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H825P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1106M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I994M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K229E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K251T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K525R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K876K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1151L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1184L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L281I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L355L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L508V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L581L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | N66N | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P195A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q498Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R1160H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1011L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1292L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S778* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V719M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V904V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Y891C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A593T | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1168N | Missense | 1 |
| BRCA | Breast invasive carcinoma | D430G | Missense | 1 |
| BRCA | Breast invasive carcinoma | D552E | Missense | 1 |
| BRCA | Breast invasive carcinoma | P676R | Missense | 1 |
| CESC | Cervical and endocervical cancers | E155Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E306K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E330* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | S1332L | Missense | 1 |
| CESC | Cervical and endocervical cancers | V1078V | Silent | 1 |
| COAD | Colon adenocarcinoma | A606T | Missense | 1 |
| COAD | Colon adenocarcinoma | C1191Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D634G | Missense | 1 |
| COAD | Colon adenocarcinoma | E1087E | Silent | 1 |
| COAD | Colon adenocarcinoma | E474D | Missense | 1 |
| COAD | Colon adenocarcinoma | E642K | Missense | 1 |
| COAD | Colon adenocarcinoma | I1127V | Missense | 1 |
| COAD | Colon adenocarcinoma | L183R | Missense | 1 |
| COAD | Colon adenocarcinoma | M397T | Missense | 1 |
| COAD | Colon adenocarcinoma | N1090N | Silent | 1 |
| COAD | Colon adenocarcinoma | P1281H | Missense | 1 |
| COAD | Colon adenocarcinoma | P676P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1334G | Missense | 1 |
| COAD | Colon adenocarcinoma | R1334R | Silent | 1 |
| COAD | Colon adenocarcinoma | S1302L | Missense | 1 |
| COAD | Colon adenocarcinoma | S376Y | Missense | 1 |
| COAD | Colon adenocarcinoma | S580S | Silent | 1 |
| COAD | Colon adenocarcinoma | T551T | Silent | 1 |
| COAD | Colon adenocarcinoma | T566M | Missense | 1 |
| COAD | Colon adenocarcinoma | V337M | Missense | 1 |
| ESCA | Esophageal carcinoma | Q490H | Missense | 1 |
| ESCA | Esophageal carcinoma | Q982H | Missense | 1 |
| GBM | Glioblastoma multiforme | S1266S | Silent | 1 |
| GBM | Glioblastoma multiforme | V732V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A593A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D543V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F922C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G109W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H715L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I117I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1300T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P999S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1143R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S172C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G434R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T1311I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V1190L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V512V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G942W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P636P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R468S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T1007A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V472A | Missense | 1 |
| LUAD | Lung adenocarcinoma | C730R | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1098D | Silent | 1 |
| LUAD | Lung adenocarcinoma | D645D | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1031Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E285D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G286G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G865C | Missense | 1 |
| LUAD | Lung adenocarcinoma | H715Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | K398N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K912K | Silent | 1 |
| LUAD | Lung adenocarcinoma | P1132L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P137L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1081S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R85L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1332L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S629S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S770S | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y792C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E542D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S377S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E1087Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R1334R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A283T | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | W275L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1008A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A1130T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A270T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A827T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A934V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D1286D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | L179L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R1126H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R85G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1155M | Missense | 1 |
| READ | Rectum adenocarcinoma | E1087G | Missense | 1 |
| READ | Rectum adenocarcinoma | E646K | Missense | 1 |
| READ | Rectum adenocarcinoma | N157Y | Missense | 1 |
| SARC | Sarcoma | A797V | Missense | 1 |
| SARC | Sarcoma | L1184L | Silent | 1 |
| SARC | Sarcoma | P75L | Missense | 1 |
| SARC | Sarcoma | P919S | Missense | 1 |
| SARC | Sarcoma | Q265Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A320A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F918F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G288E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G419R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G942R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1005I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M21R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P72L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P905P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P938S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S11F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S177F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S376F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S376S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S84F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A374A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1323R | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1204G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1099K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1049G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G523E | Missense | 1 |
| STAD | Stomach adenocarcinoma | I1097I | Silent | 1 |
| STAD | Stomach adenocarcinoma | I143S | Missense | 1 |
| STAD | Stomach adenocarcinoma | I562I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K174T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K582K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L1298I | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1132T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P416S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1227R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1320Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1355W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R501C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R600Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R935* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S1332L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S678N | Missense | 1 |
| STAD | Stomach adenocarcinoma | V264I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V831M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y249Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | R1273W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A934A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C845* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D417N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D543N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D69N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D77N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1064D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E917* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F757F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1248G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1108H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I27N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I860I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1228H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1353W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R260C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R42H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R501H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R526I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R602W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R755Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V829I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W1358R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y641C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 15.7 | 11.3 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 3.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2 | 2.3 | 20 |
| COAD | Colon adenocarcinoma | 367 | 11.8 | 12.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 3.9 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.9 | 6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2 | 3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 11.8 | 9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2 | 0.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.8 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.9 | 5.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.3 | 0 |
| SARC | Sarcoma | 247 | 3.9 | 2.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.8 | 7.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.7 | 14.3 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.8 | 12.8 | 40 |