Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | D12D | Silent | 2 |
| LGG | Brain Lower Grade Glioma | A906T | Missense | 2 |
| STAD | Stomach adenocarcinoma | R917C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A599A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G403A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G656V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I774V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I91I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1077F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L185F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P182P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P339P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1114Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R940R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S674* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S782* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S801L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V35I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V3I | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1035K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1170K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G142G | Silent | 1 |
| BRCA | Breast invasive carcinoma | I271R | Missense | 1 |
| BRCA | Breast invasive carcinoma | N596N | Silent | 1 |
| BRCA | Breast invasive carcinoma | P260P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R515* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | T382P | Missense | 1 |
| CESC | Cervical and endocervical cancers | E513K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E978Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | G554E | Missense | 1 |
| CESC | Cervical and endocervical cancers | I1087I | Silent | 1 |
| CESC | Cervical and endocervical cancers | L114L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L185F | Missense | 1 |
| CESC | Cervical and endocervical cancers | L357L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R1086T | Missense | 1 |
| CESC | Cervical and endocervical cancers | R477T | Missense | 1 |
| CESC | Cervical and endocervical cancers | S226C | Missense | 1 |
| COAD | Colon adenocarcinoma | E1013K | Missense | 1 |
| COAD | Colon adenocarcinoma | G652S | Missense | 1 |
| COAD | Colon adenocarcinoma | K1109K | Silent | 1 |
| COAD | Colon adenocarcinoma | N921Y | Missense | 1 |
| COAD | Colon adenocarcinoma | Q869R | Missense | 1 |
| COAD | Colon adenocarcinoma | R1008Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1102R | Silent | 1 |
| COAD | Colon adenocarcinoma | R407C | Missense | 1 |
| COAD | Colon adenocarcinoma | S676Y | Missense | 1 |
| COAD | Colon adenocarcinoma | S887N | Missense | 1 |
| COAD | Colon adenocarcinoma | T511M | Missense | 1 |
| COAD | Colon adenocarcinoma | V962M | Missense | 1 |
| ESCA | Esophageal carcinoma | C33C | Silent | 1 |
| ESCA | Esophageal carcinoma | F903F | Silent | 1 |
| ESCA | Esophageal carcinoma | K969R | Missense | 1 |
| ESCA | Esophageal carcinoma | R388L | Missense | 1 |
| ESCA | Esophageal carcinoma | S288S | Silent | 1 |
| GBM | Glioblastoma multiforme | D905D | Silent | 1 |
| GBM | Glioblastoma multiforme | Y578C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E898D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H534Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I415V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1025L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S715L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S887C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T66A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V98V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | E658* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F127L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L185F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P300A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q606* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T1108A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y92D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A187A | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D207D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1058H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S130F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | C1046R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E172K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K259K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N623S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N646N | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1079K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E291K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E295K | Missense | 1 |
| LUAD | Lung adenocarcinoma | F903F | Silent | 1 |
| LUAD | Lung adenocarcinoma | P608P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R296K | Missense | 1 |
| LUAD | Lung adenocarcinoma | V962L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V97L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D913E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K190K | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L633F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L696F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1131P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q1129* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | V144I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G652D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | N921D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T1108N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A703A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | D620Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E787K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P789L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S725S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | I38T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E251K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F903F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H1163L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L686L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P874S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q930Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S584F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S611F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T524I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V337I | Missense | 1 |
| STAD | Stomach adenocarcinoma | E140E | Silent | 1 |
| STAD | Stomach adenocarcinoma | E230D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1189S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G419A | Missense | 1 |
| STAD | Stomach adenocarcinoma | G765G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G994E | Missense | 1 |
| STAD | Stomach adenocarcinoma | H1032H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K564E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L107L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P445Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | P489H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P632Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1003Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R216C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R306H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R503G | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | M934R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E140G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E239* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E251* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F1066F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F618L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1159D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1060R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1112N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L107L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N247D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1009S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P310Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P798P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P948L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R388Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R476* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R476Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S537Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T817T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V3I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14 | 7.8 | 22.2 |
| BRCA | Breast invasive carcinoma | 976 | 7 | 3.9 | 11.1 |
| CESC | Cervical and endocervical cancers | 194 | 7 | 6.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.3 | 9.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 7 | 2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.3 | 1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.7 | 5.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 4.9 | 22.2 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.7 | 3.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.7 | 2.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.7 | 5.9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.7 | 3.9 | 11.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.7 | 2.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7 | 6.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.3 | 13.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.3 | 12.7 | 33.3 |