Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E398E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E637Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G491A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G681S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K956N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L324L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L65P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L930L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P798R | Missense | 1 |
| BRCA | Breast invasive carcinoma | E620* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G37R | Missense | 1 |
| BRCA | Breast invasive carcinoma | H748H | Silent | 1 |
| BRCA | Breast invasive carcinoma | R560W | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y337F | Missense | 1 |
| CESC | Cervical and endocervical cancers | E821Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E843D | Missense | 1 |
| CESC | Cervical and endocervical cancers | K743K | Silent | 1 |
| CESC | Cervical and endocervical cancers | L924L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R742R | Silent | 1 |
| CESC | Cervical and endocervical cancers | S109C | Missense | 1 |
| COAD | Colon adenocarcinoma | A943T | Missense | 1 |
| COAD | Colon adenocarcinoma | A971T | Missense | 1 |
| COAD | Colon adenocarcinoma | D639G | Missense | 1 |
| COAD | Colon adenocarcinoma | E638D | Missense | 1 |
| COAD | Colon adenocarcinoma | G304G | Silent | 1 |
| COAD | Colon adenocarcinoma | P407H | Missense | 1 |
| COAD | Colon adenocarcinoma | P435P | Silent | 1 |
| COAD | Colon adenocarcinoma | P465S | Missense | 1 |
| COAD | Colon adenocarcinoma | R174C | Missense | 1 |
| COAD | Colon adenocarcinoma | R385Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R421Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R674C | Missense | 1 |
| COAD | Colon adenocarcinoma | S98S | Silent | 1 |
| ESCA | Esophageal carcinoma | A312T | Missense | 1 |
| ESCA | Esophageal carcinoma | G576G | Silent | 1 |
| ESCA | Esophageal carcinoma | L148L | Silent | 1 |
| ESCA | Esophageal carcinoma | R352H | Missense | 1 |
| ESCA | Esophageal carcinoma | Y936* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A15T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L25L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L628L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P10P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S470C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S863S | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S866G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A15T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P599P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | V32A | Missense | 1 |
| LUAD | Lung adenocarcinoma | A146D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E723K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G750E | Missense | 1 |
| LUAD | Lung adenocarcinoma | G959R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P123L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1006T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T353T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V872L | Missense | 1 |
| LUAD | Lung adenocarcinoma | W707* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | D905E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1005E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G393V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G834W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S397C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D639D | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P123S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R421W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R616C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E650D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P392P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S752A | Missense | 1 |
| READ | Rectum adenocarcinoma | T586R | Missense | 1 |
| SARC | Sarcoma | R617H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A557V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A818D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E645K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G565R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G680E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H726H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K518K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L948L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P188S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P811L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P981S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P994S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1001K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R168C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R727* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R764C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S827F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S842F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S842S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S94F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A222A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A682V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A789T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A912A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A958V | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1010G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K1009R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L140P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L59P | Missense | 1 |
| STAD | Stomach adenocarcinoma | P435L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P923P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P935S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R258Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S92S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T554M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T81T | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Y667* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A572V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A712V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A971V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C311Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D730Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E645K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G834E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G897W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P278T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P407L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P456P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R520* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R624H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.4 | 7.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.1 | 3.6 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 9.4 | 3.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.4 | 12 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 2.4 | 16.7 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 2.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.1 | 2.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.1 | 8.4 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.1 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.1 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.1 | 2.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 18.1 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 18.8 | 12 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 16.7 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.1 | 13.3 | 16.7 |