Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | S46G | Missense | 5 |
| SKCM | Skin Cutaneous Melanoma | F155F | Silent | 2 |
| STAD | Stomach adenocarcinoma | E267D | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E166K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E265K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E272K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E76K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K244E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R148I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S189C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V134A | Missense | 1 |
| BRCA | Breast invasive carcinoma | G293E | Missense | 1 |
| BRCA | Breast invasive carcinoma | N260K | Missense | 1 |
| BRCA | Breast invasive carcinoma | N319T | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q32* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | D144N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E75K | Missense | 1 |
| COAD | Colon adenocarcinoma | D144N | Missense | 1 |
| COAD | Colon adenocarcinoma | E195* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E267D | Missense | 1 |
| COAD | Colon adenocarcinoma | E302K | Missense | 1 |
| COAD | Colon adenocarcinoma | E56A | Missense | 1 |
| COAD | Colon adenocarcinoma | G143G | Silent | 1 |
| COAD | Colon adenocarcinoma | G157G | Silent | 1 |
| COAD | Colon adenocarcinoma | K205N | Missense | 1 |
| COAD | Colon adenocarcinoma | S46S | Silent | 1 |
| ESCA | Esophageal carcinoma | C338Y | Missense | 1 |
| ESCA | Esophageal carcinoma | L333V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D253N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E195* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G301G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K176E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P97P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | C338Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A313A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | F155I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I161V | Missense | 1 |
| LUAD | Lung adenocarcinoma | E75E | Silent | 1 |
| LUAD | Lung adenocarcinoma | K271Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | N70Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | W112C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y68C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A351D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V104V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | W30C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S46I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S66S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A285T | Missense | 1 |
| READ | Rectum adenocarcinoma | C245C | Silent | 1 |
| READ | Rectum adenocarcinoma | E4D | Missense | 1 |
| READ | Rectum adenocarcinoma | S147* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | S45L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D253D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G295R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H146Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K238E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L269V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L39L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S149L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T266T | Silent | 1 |
| STAD | Stomach adenocarcinoma | E302K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E4A | Missense | 1 |
| STAD | Stomach adenocarcinoma | K345T | Missense | 1 |
| STAD | Stomach adenocarcinoma | M276T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F155F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G132E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R67I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 15.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.7 | 25 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 18.8 | 18.9 | 25 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 3.8 | 25 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.2 | 3.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.2 | 7.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.2 | 3.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 6.2 | 1.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.2 | 3.8 | 25 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 31.2 | 9.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 11.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.2 | 3.8 | 0 |