Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D255H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1088N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D266H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D555H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E241* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E252K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E943K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G75E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I873M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1172L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L553L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L749L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R315R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S172F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S294* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | A391V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1212V | Missense | 1 |
| BRCA | Breast invasive carcinoma | P92L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q738H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1041W | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1188* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | Y1161Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | Y1303C | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1304L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L446L | Silent | 1 |
| CESC | Cervical and endocervical cancers | P16T | Missense | 1 |
| CESC | Cervical and endocervical cancers | R293C | Missense | 1 |
| CESC | Cervical and endocervical cancers | R637W | Missense | 1 |
| CESC | Cervical and endocervical cancers | T62T | Silent | 1 |
| COAD | Colon adenocarcinoma | A230A | Silent | 1 |
| COAD | Colon adenocarcinoma | D931N | Missense | 1 |
| COAD | Colon adenocarcinoma | E1023G | Missense | 1 |
| COAD | Colon adenocarcinoma | E652D | Missense | 1 |
| COAD | Colon adenocarcinoma | G455V | Missense | 1 |
| COAD | Colon adenocarcinoma | H472H | Silent | 1 |
| COAD | Colon adenocarcinoma | K357K | Silent | 1 |
| COAD | Colon adenocarcinoma | P1022P | Silent | 1 |
| COAD | Colon adenocarcinoma | P1022S | Missense | 1 |
| COAD | Colon adenocarcinoma | P497T | Missense | 1 |
| COAD | Colon adenocarcinoma | R1091C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1098C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1294R | Silent | 1 |
| COAD | Colon adenocarcinoma | R551C | Missense | 1 |
| COAD | Colon adenocarcinoma | T1184T | Silent | 1 |
| COAD | Colon adenocarcinoma | V844I | Missense | 1 |
| ESCA | Esophageal carcinoma | A1105A | Silent | 1 |
| ESCA | Esophageal carcinoma | A230T | Missense | 1 |
| ESCA | Esophageal carcinoma | D69N | Missense | 1 |
| ESCA | Esophageal carcinoma | G22V | Missense | 1 |
| ESCA | Esophageal carcinoma | P16T | Missense | 1 |
| ESCA | Esophageal carcinoma | P234Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R441W | Missense | 1 |
| ESCA | Esophageal carcinoma | T1244T | Silent | 1 |
| GBM | Glioblastoma multiforme | L470P | Missense | 1 |
| GBM | Glioblastoma multiforme | R430R | Silent | 1 |
| GBM | Glioblastoma multiforme | R740H | Missense | 1 |
| GBM | Glioblastoma multiforme | V844V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D276N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E704D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1018G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1127D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K357K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P274P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q684P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1124W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1294C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S54L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V844I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y1319C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N987S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P50P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q757K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R43* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S192G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1105T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1353V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A404A | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D405D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P465P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1098C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T1027S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V871V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | W1074C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L663L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R544G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S891P | Missense | 1 |
| LUAD | Lung adenocarcinoma | A722E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E937* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G1114C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1270S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G586V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L711L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L906F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P137H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P284H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P823P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P992A | Missense | 1 |
| LUAD | Lung adenocarcinoma | R327C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1049Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | S348* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S777* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | T1163S | Missense | 1 |
| LUAD | Lung adenocarcinoma | T14T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V1075L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E122K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E161K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H429P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K831N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L1019L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P48P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S426S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T503T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T795S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | C883* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P93A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1105V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K233T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | F1220V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N1154K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P1296R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P1296T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1294C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R242H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R975* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | L1014L | Silent | 1 |
| SARC | Sarcoma | A1080A | Silent | 1 |
| SARC | Sarcoma | P396S | Missense | 1 |
| SARC | Sarcoma | P403L | Missense | 1 |
| SARC | Sarcoma | P403P | Silent | 1 |
| SARC | Sarcoma | V1261V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E644E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E937K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1013F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G321G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G75E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G800G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L646L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P137L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P173S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P813S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q684H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S172S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T462I | Missense | 1 |
| STAD | Stomach adenocarcinoma | C412Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1316N | Missense | 1 |
| STAD | Stomach adenocarcinoma | G972V | Missense | 1 |
| STAD | Stomach adenocarcinoma | K250K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L1179L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P766P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q884E | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1184A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1184M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T565T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T795S | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L66P | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R283R | Silent | 1 |
| THYM | Thymoma | C615* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1080V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A228V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C450C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1340N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H880Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K233K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K364N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1044F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L662L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L748I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1004H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1274Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1276I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1350H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R617C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R647* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R750H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1052A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S148Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S186S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S596G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S8S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1060T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1084P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V611L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y496C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.3 | 8.5 | 18.2 |
| BRCA | Breast invasive carcinoma | 976 | 1.8 | 5.1 | 9.1 |
| CESC | Cervical and endocervical cancers | 194 | 5.5 | 2.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.9 | 8.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.6 | 5.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 3.6 | 1.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.5 | 7.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.8 | 1.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 9.1 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.3 | 4.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 1.8 | 1.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.5 | 10.2 | 27.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.3 | 4.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.8 | 9.1 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 5.1 | 9.1 |
| READ | Rectum adenocarcinoma | 122 | 1.8 | 0 | 0 |
| SARC | Sarcoma | 247 | 5.5 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 10.9 | 5.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 7.3 | 5.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 1.8 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 9.1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.9 | 16.1 | 9.1 |