Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | F1230F | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A367A | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D664Y | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A407T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E175K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F298L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1143T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1291F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L370L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L436V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P84S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q68* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S459F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S633* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V211V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E1171Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E851* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | H322N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L978V | Missense | 1 |
| BRCA | Breast invasive carcinoma | S337L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E810D | Missense | 1 |
| CESC | Cervical and endocervical cancers | L789W | Missense | 1 |
| COAD | Colon adenocarcinoma | A367V | Missense | 1 |
| COAD | Colon adenocarcinoma | C141Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D1229N | Missense | 1 |
| COAD | Colon adenocarcinoma | F1147V | Missense | 1 |
| COAD | Colon adenocarcinoma | G455D | Missense | 1 |
| COAD | Colon adenocarcinoma | K223R | Missense | 1 |
| COAD | Colon adenocarcinoma | K660N | Missense | 1 |
| COAD | Colon adenocarcinoma | K96T | Missense | 1 |
| COAD | Colon adenocarcinoma | N1259K | Missense | 1 |
| COAD | Colon adenocarcinoma | R1016H | Missense | 1 |
| COAD | Colon adenocarcinoma | R510* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R575Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S117P | Missense | 1 |
| COAD | Colon adenocarcinoma | S142S | Silent | 1 |
| COAD | Colon adenocarcinoma | T1311I | Missense | 1 |
| COAD | Colon adenocarcinoma | V309F | Missense | 1 |
| COAD | Colon adenocarcinoma | V78A | Missense | 1 |
| COAD | Colon adenocarcinoma | Y748Y | Silent | 1 |
| ESCA | Esophageal carcinoma | E1237Q | Missense | 1 |
| ESCA | Esophageal carcinoma | E175E | Silent | 1 |
| ESCA | Esophageal carcinoma | G66D | Missense | 1 |
| ESCA | Esophageal carcinoma | I145V | Missense | 1 |
| ESCA | Esophageal carcinoma | P148A | Missense | 1 |
| ESCA | Esophageal carcinoma | Q1255E | Missense | 1 |
| ESCA | Esophageal carcinoma | R564* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R684G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I1187S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L114L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1275L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L130L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M1220I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q372* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q372H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q68* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1199N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y241H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A470S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M672K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V801V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y990D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A367V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L686* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q1159Q | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S1047L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T1228T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D670Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K694R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R402H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T363A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1129R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1294S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A72A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D201Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | G110* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G7C | Missense | 1 |
| LUAD | Lung adenocarcinoma | P675S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R486* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S337* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | T109S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V319A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D150H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P133L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S111C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I770S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K223K | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | N527S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S244I | Missense | 1 |
| READ | Rectum adenocarcinoma | E616Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1231K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1166F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1243R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L502F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P248L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P330S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P379P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q354* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1312F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S159P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S73A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T326I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T326T | Silent | 1 |
| STAD | Stomach adenocarcinoma | C499* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | D28G | Missense | 1 |
| STAD | Stomach adenocarcinoma | F1188V | Missense | 1 |
| STAD | Stomach adenocarcinoma | F1274C | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1297R | Missense | 1 |
| STAD | Stomach adenocarcinoma | M546T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N290N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P695P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R203Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1135I | Missense | 1 |
| STAD | Stomach adenocarcinoma | T708A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A262T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A995A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1125K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1231K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1266* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E941* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G391R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G512E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I401V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K179Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K223N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K673R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N784S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P526P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q318Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R510* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R737I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1121S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S142S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S366L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T424I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.1 | 8.5 | 12.5 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.3 | 6.2 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.1 | 16 | 6.2 |
| ESCA | Esophageal carcinoma | 185 | 3.6 | 6.4 | 6.2 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10.7 | 5.3 | 12.5 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.6 | 3.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 7.1 | 2.1 | 6.2 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.6 | 1.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.6 | 5.3 | 18.8 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.6 | 3.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 17.9 | 9.6 | 6.2 |
| STAD | Stomach adenocarcinoma | 393 | 7.1 | 8.5 | 6.2 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 25 | 16 | 18.8 |